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2008 - Factores de crecimiento hematopoyético-Dr. A. Biete - GICOR

2008 - Factores de crecimiento hematopoyético-Dr. A. Biete - GICOR

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COMENTARIOS EORTC-GUIDELINES<br />

EORTC GUIDELINES<br />

A DIVERSOS ESTUDIOS<br />

1. Henke et al. ORL. Señalan diversas irregularida<strong>de</strong>s<br />

y que los datos han suscitado controversia y<br />

amplias discusiones (cartas cartas al director, etc.).<br />

Lancet<br />

2. Bokkel et al. (1998). Ovario. Ovario.<br />

13% progresión<br />

(brazo brazo EPO) vs 6% (control). “This was thought to<br />

reflect the higher proportion of patients with stage<br />

II rather than stage III/IV disease in the control<br />

group”. Med. Oncol. Oncol<br />

3. Leyland-Jones Leyland Jones et al (2003) Mama M 1 en QT. Se<br />

interrumpe por mortalidad en brazo EPO. (6% vs<br />

3%).<br />

”The authors comment that this study suffered<br />

problems in <strong>de</strong>sign, conduct and post-trial post trial analysis,

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