Anti-inflammatoires non-stéroïdiens (AINS) et paracétamol:
Anti-inflammatoires non-stéroïdiens (AINS) et paracétamol:
Anti-inflammatoires non-stéroïdiens (AINS) et paracétamol:
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Conventional NSAIDs<br />
heme<br />
COX-1<br />
tyrosine at 385<br />
Kurumbail RG <strong>et</strong> al. Nature 1996;384:644-8.<br />
+<br />
arginine at 120<br />
inhibit both COX-1 and COX-2<br />
COX-2<br />
tyrosine at 385<br />
arginine at 120<br />
binding to Arg 120<br />
through carboxyalate is enough...<br />
2009-2010 <strong>AINS</strong> <strong>et</strong> parac<strong>et</strong>amol 38<br />
+
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