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7. Hidden Markov Models (Parte 2) (pdf, it, 413 KB, 4/28/10)

7. Hidden Markov Models (Parte 2) (pdf, it, 413 KB, 4/28/10)

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Pair hidden <strong>Markov</strong> models<br />

V<strong>it</strong>torio Murino Riconoscimento e Classificazione per la Bioinformatica 86<br />

86<br />

Problema dell’allineamento di<br />

sequenze<br />

• INPUT: Due sequenze su di un alfabeto ∑ (4<br />

nucleotidi or 20 aminoacidi):<br />

ATGTTAT e ATCGTAC<br />

• OUTPUT: Inserendo ‘-’ e shiftando le due<br />

sequenze devo produrre due sequenze allineate<br />

della stessa lunghezza<br />

A T - G T T A T<br />

A T C G T - A C<br />

V<strong>it</strong>torio Murino Riconoscimento e Classificazione per la Bioinformatica 87<br />

87<br />

20

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