04 Lezione dalla 4 alla 7 Modulo 2 - ctf novara
04 Lezione dalla 4 alla 7 Modulo 2 - ctf novara
04 Lezione dalla 4 alla 7 Modulo 2 - ctf novara
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Chemokine biological activities<br />
Chemotaxis-related<br />
Leukocyte recruitment:<br />
1 leukocyte adhesion (CX3CL1)<br />
2 integrin activation Amplification of immune responses (innate and specific)<br />
3 leukocyte guidance in tissues<br />
Chemotaxis-unrelated<br />
- Modulation of angiogenesis and fibrosis<br />
- Modulation of differentiation and proliferation of hematopoietic precursors<br />
- Role in ontogeny (CNS and vasculature)<br />
- Control of cell survival<br />
- Phagocyte activation and T cell costimulation<br />
- Gene expression regulation
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