04 Lezione dalla 4 alla 7 Modulo 2 - ctf novara
04 Lezione dalla 4 alla 7 Modulo 2 - ctf novara
04 Lezione dalla 4 alla 7 Modulo 2 - ctf novara
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Maturazione dei fagociti mononucleati<br />
Monocytes are 10 to 15 μm in diameter, and they have bean-shaped nuclei and finely granular cytoplasm containing<br />
lysosomes, phagocytic vacuoles, and cytoskeletal filaments.<br />
Once they enter tissues, monocytes cells mature and become macrophages. Macrophages may assume different morphologic<br />
forms after activation by external stimuli, such as microbes. Some develop abundant cytoplasm and are called epithelioid<br />
cells because of their resemblance to epithelial cells of the skin.<br />
Activated macrophages can fuse to form multinucleate giant cells.<br />
Macrophages in different tissues have been given special names to designate specific locations. For instance, in the central<br />
nervous system, they are called microglial cells; when lining the vascular sinusoids of the liver, they are called Kupffer<br />
cells; in pulmonary airways, they are called alveolar macrophages; and multinucleate phagocytes in bone are called<br />
Downloaded from: StudentConsult (on 18 November 2008 08:08 PM)<br />
osteoclasts.<br />
© 2005 Elsevier
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