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Gli studi di coorte - Centro per lo Studio e la Prevenzione ...

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Framingham Heart Study<br />

1948 nel<strong>la</strong> città <strong>di</strong> Framingham: identificati 5.209 residenti sani (M/ F) <strong>di</strong> età 30-62 anni;<br />

Al baseline ed ogni 2 anni: vista me<strong>di</strong>ca approfon<strong>di</strong>ta, raccolta <strong>di</strong> informazioni<br />

sulle pato<strong>lo</strong>gie pregresse e sul<strong>lo</strong> stile <strong>di</strong> vita e test <strong>di</strong> <strong>la</strong>boratorio<br />

1971 Offspring study<br />

1994 Omni cohort<br />

2002 Third generation cohort<br />

2003 Omni cohort 2<br />

1960 Cigarette smoking found to increase the risk of heart <strong>di</strong>sease<br />

1961 Cholesterol level, b<strong>lo</strong>od pressure, and electrocar<strong>di</strong>ogram abnormalities found to increase the<br />

risk of heart <strong>di</strong>sease<br />

1967 Physical activity found to reduce the risk of heart <strong>di</strong>sease and obesity to increasethe risk<br />

1970 High b<strong>lo</strong>od pressure found to increase the risk of stroke<br />

-------<br />

1988 High levels of HDL cholesterol found to reduce risk of death<br />

-------<br />

2009 A new genetic variant associated with increased susceptibility for atrial fibril<strong>la</strong>tion, a prominent<br />

risk factor for stroke and heart failure, is reported in two <strong>stu<strong>di</strong></strong>es based on data from the<br />

Framingham Heart Study.<br />

2009 parental dementia may lead to poor memory in middle-aged adults.<br />

www.framingham.com

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