preparatis samedicino gamoyenebis instruqcia ko-reniteki
preparatis samedicino gamoyenebis instruqcia ko-reniteki
preparatis samedicino gamoyenebis instruqcia ko-reniteki
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hidrolizis xangrZlivoba msgavsia sxvadasxva re<strong>ko</strong>mendebuli Terapiuli dozebis<br />
dros.<br />
hidroqloroTiazidi<br />
hidroqloroTiazidis T 1/2 5,6-dan 14,8 saaTamde. ar ganicdis metabolizms, magram<br />
swrafad gamoiyofa Tirkmelebis saSualebiT. SigniT miRebuli dozis aranakleb 61%<br />
ucvleli saxiT gamoiyofa 24 saaTis manZilze. hidroqloroTiazidi aRwevs<br />
placentaSi, magram ar aRwevs hematoencefalur barierSi.<br />
enalapril maleatisa da hidroqloroTiazidis <strong>ko</strong>mbinacia<br />
enalaprilisa da hidroqloroTiazidis mravaljeradi miReba ar axdens gavlenas (an<br />
mxolod umniSvnelod) <strong>preparatis</strong> TiToeuli <strong>ko</strong>mponentis bioSeRwevadobaze. preparat<br />
<strong>ko</strong>-<strong>reniteki</strong>s <strong>ko</strong>mbinirebuli tabletis miReba misi ingredientebis calkeuli wamlis<br />
formiT erTdrouli miRebis bioeqvivalenturia.<br />
miRebis Cveneba<br />
arteriuli hipertenzia (pacientTaTvis, romlebisTvisac naCvenebia <strong>ko</strong>mbinirebuli<br />
Terapia).<br />
ukuCveneba<br />
- hipermgrZnobeloba <strong>preparatis</strong> nebismieri <strong>ko</strong>mponentis mimarT;<br />
- hipermgrZnobeloba sulfonamidebis mimarT;<br />
- anamnezSi angionevrozuli SeSupeba, romelic dakavSirebulia agf<br />
inhibitorebis daniSvnasTan, aseve genetikuri an idiopaTuri angionevrozuli<br />
SeSupeba;<br />
- 18 wlamde asakis pacientTaTvis (usafrTxoeba da efeqturoba ar aris<br />
dadgenili);<br />
- anuria;<br />
- hemodializi Tirkmlis ukmarisobis mqone pacientTa SemTxvevaSi.<br />
sifrTxiliT<br />
aortaluri stenozi, cerebrovaskularuli daavadeba (maT Soris Tavis tvinis<br />
sisxlis mimoqcevis ukmarisoba), gulis iSemiuri daavadeba, gulis qronikuli<br />
ukmarisoba, SemaerTebeli qsovilis mwvave autoimunuri sistemuri daavadeba (maT<br />
Soris sistemuri wiTeli mglura, sklerodermiti), Zvlis tvinis sisxlwarmoqmnis<br />
daTrgunva, Saqriani diabeti, hiperkaliemia, Tirkmlis arteriis ormxrivi stenozi,<br />
mdgomareoba Tirkmlis transplantaciis Semdeg, Tirkmlis da/an RviZlis ukmarisoba,<br />
natriumis SemzRudveli dieta, mdgomareoba, romelsac Tan axlavs cirkulirebadi<br />
sisxlis moculobis Semcireba (maT Soris diarea, Rebineba), xandazmuli asaki.<br />
miReba fexmZimobis dros<br />
re<strong>ko</strong>mendebuli ar aris <strong>preparatis</strong> gamoyeneba fexmZimobis dros. fexmZimobis<br />
dadgenisaTanave Sewyvetil unda iqnas preparat <strong>ko</strong>-<strong>reniteki</strong>s miReba. gamonakliss<br />
warmoadgens is SemTxvevebi, rodesac <strong>preparatis</strong> miRebas dedisTvis sasicocxlo<br />
mniSvneloba aqvs. <strong>preparatis</strong> fexmZimobis meore da mesame trimestris dros miRebis<br />
SemTxvevaSi, agf inhibitorebi nayofis an Cvilis daavadebas an sikvdils iwvevs. am<br />
periodis ganmavlobaSi agf inhibitorebis gamoyenebas uaryofiTi gavlena aqvs<br />
nayofsa da Cvilze, kerZod, arteriuli wnevis vardna, Tirkmlis ukmarisoba,<br />
hiperkaliemia da/an Cvilis Tavis qalis hipoplazia. SesaZlebelia oligohidramnionis<br />
Camoyalibeba, rac, rogorc wesi, Tirkmlis funqciis klebis Sedegadaa mosalodneli.<br />
es daavadeba iwvevs kidurebis <strong>ko</strong>ntraqturas, Tavis qalis deformacias, maT Soris,<br />
saxis nawilis, filtvebis hipoplazias.<br />
re<strong>ko</strong>mendebuli ar aris fexmZimobis dros diurezulebis gamoyeneba, rameTu SesaZloa<br />
gamoiwvios nayofisa da axalSobilis siyviTle, Trombocitopenia da, mozrdil<br />
pacientTa msgavsad, sxva gverdiTi efeqtebi. <strong>preparatis</strong> fexmZimobis dros <strong>gamoyenebis</strong><br />
aucileblobis SemTxvevaSi, pacienti gafrTxilebul unda iqnas mosalodneli<br />
safrTxis Sesaxeb. im iSviaT SemTxvevaSi, rodesac <strong>preparatis</strong> daniSvna aucilebeli<br />
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