preparatis samedicino gamoyenebis instruqcia ko-reniteki
preparatis samedicino gamoyenebis instruqcia ko-reniteki
preparatis samedicino gamoyenebis instruqcia ko-reniteki
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saWmlis momnelebeli organoTa sistema: pankreatiti, diarea, Rebineba, dispefsia,<br />
tkivili muclis areSi, meteorizmi, yabzoba.<br />
centraluri nervuli sistema:<br />
uZiloba, Zilianoba, paresTeziebi, momatebuli nervuli agznebadoba.<br />
sasunTqi sistema:<br />
qoSini.<br />
kanis safari:<br />
stivens-jonsonis sindromi, kanis gamonayari, qavili, hiperhidrozi.<br />
sxva:<br />
Tirkmlis funqciis moSla, Tirkmlis ukmarisoba, libidos Sesusteba, simSrale piris<br />
RruSi, podagra, Suili yurebSi, arTralgia.<br />
aRweril iqna sindromebis <strong>ko</strong>mpleqsi, romelic Seicavs cxelebas, serozits,<br />
vaskulits, mialgias/miozits, arTralgias/arTrits, dadebiTi testi antinukleur<br />
antisxeulebze, eriTrocitebis dagrovebis siswrafis momateba, eozinofilia da<br />
lei<strong>ko</strong>citozi. SesaZloa gamovlindes fotosensibilizacia.<br />
alergiuli reaqciebi / angionevrozuli SeSupeba:<br />
saxis, kidurebis, tuCebis, enis, xmovani iogebis, kidurebis da/an saylapavis<br />
angionevrozuli SeSupebis SemTxveva Zalze iSviaTad gamovlenila (ix.<br />
gansakuTrbuli miTiTebebi). aseve iSviaTad gamovlenila intersticiuli<br />
angionevrozuli SeSupeba, romelic dakavSirebulia agf inhibitorebis miRebasTan,<br />
maT Soris, enalaprilTan.<br />
laboratoriuli maCveneblebi:<br />
hiperkaliemia, hiperurikemia da hipokaliemia. aRiniSna aseve Sratis kreatininis<br />
<strong>ko</strong>ncentraciis da RviZlis fermentebis aqtivobisa da/an Sratis bilirubinis<br />
momateba. es maCveneblebi, rogorc wesi, normalizdeboda <strong>ko</strong>-<strong>reniteki</strong>T mkurnalobis<br />
dasrulebis Semdeg. aRiniSna hemoglobinisa da hematokritis maCveneblebis daweva.<br />
Warbi doza<br />
simptomebi:<br />
enalapril maleati<br />
arteriuli wnevis gamoxatuli dacema, romelic <strong>preparatis</strong> miRebidan daaxloebiT 6<br />
saaTis Semdeg iwyeba. sisxlis plazmaSi enalaprilatis <strong>ko</strong>ncentracia, romelic 100-<br />
200-jer aRemateba Terapiuli dozis daniSvnis Sedegad Camoyalibebul <strong>ko</strong>ncentracias,<br />
aRiniSna Sesabamisad 300 da 440 mg enalaprilis miRebis Semdeg.<br />
hidroqloroTiazidi<br />
simptomatika, gamowveuli eleqtrolitebis dakargviTa (hipokaliemia, hipoqloremia,<br />
hipoanatriemia) da dehidtrataciiT Warbi diurezis gamo. Tu pacienti adre<br />
digitalisis preparatebs Rebulobda, hipokaliemiam, SesaZloa, ariTmia gamoiwvios.<br />
mkurnaloba<br />
ar arsebobs specifiuri monacemebi <strong>preparatis</strong> Warbi dozis miRebis samkurnalod.<br />
pacienti eqimis mkacri <strong>ko</strong>ntrolis qveS unda imyofebodes, mkurnaloba dauyovnebliv<br />
unda iqnas Sewyvetili. mkurnaloba – simptomaturi. gadaudebel zomad SeiZleba<br />
CaiTvalos kuWis amorecxva, Tuki preparati cota xnis winaa miRebuli, aseve<br />
dehidrataciis, eleqtrolituri balansisa da arteriuli wnevis mkveTri dawevis<br />
<strong>ko</strong>reqcia sayovelTaod gavrcelebuli meTodebis gamoyenebiT: 0.9% natriumis<br />
qloridis xsnaris Sinagani infuzia. efeqturia, aseve, angiotenzin II-s Seyvana.<br />
enalaprilatis gamoyvana sisxlismimoqcevis sistemidan SesaZlebelia hemodializis<br />
saSualebiT (ix. gansakuTrebuli miTiTebebi, hemodializze myofi pacientebi).<br />
urTierTqmedeba sxva samkurnalo saSualebebTan<br />
sxva hipotenziuri saSualebebi<br />
enalaprilis sxva hipotenziur saSualebebTan daniSnvisas SesaZloa aRiniSnos<br />
efeqtis sumireba.<br />
5
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