vazobrali (Vasobral) gamoyenebis instruqcia generiuli dasaxeleba ...

vazobrali(Vasobral)gamoyenebis instruqciaÀÌÏÚÄÍÄÁÉÓ ÉÍÓÔÒÖØÝÉÀgeneriuli dasaxeleba:Dihydroergocryptine A mesilate ; Caffeinewamlis forma:tabletiSemadgenloba:aqtiuri nivTiereba:1 tableti Seicavs 4 mg dihidroergokiptinis a mezilats; 40 mgkofeins.damxmare nivTierebebi:limonmJava, 95%-iani eTanoli, glicerini, gasufTavebuli wyali.farmakologiuri moqmedeba:preparatis SemadgenloabSi Semavali dihidrirebuli Wvavis rqiswarmoebuli alfa-dihidroergokriptini TrgunavssisxlZarRvebis gluvkunTovani ujredebis alfa 1 da alfa 2adrenoreceptorebs. igi cns-is dopaminergul daserotoninergul receptorebze avlens mastimulirebelzemoqmedebas.preparatis gamoyenebisas mcirdeba Trombocitebisa daeriTrocitebis agregacia, sisxlZarRvebis kedlebis ganvladoba,Tavis tvinSi umjobesdeba sisxlimimoqceva da metaboluriprocesebi, matulobs Tavis tvinis qsovilis rezistentobahipoqsiis mimarT.kofeini avlens cns-ze mastimulirebel moqmedebas, ZiriTadadTavis tvinis qerqze, sunTqvisa da hipoqsiis mimarTvazomotorul centrebze. preparati aumjobesebs gonebriv dafizikur Sromisunarianobas. igi amcirebs daRlilobis SegrZnebasda avlens gul-sisxlZarRvTa sistemaze mastimulirebelzemoqmedebas: zrdis gulis SekumSvis sixSiresa da Zalas,arteriuli hipotenziis dros maRla swevs arteriul wnevas.

farmakokinetika:preparatis SemadgenlobaSi Semavali alfa-dihidroergokriptiniswrafad (15-20 wT-is ganmavlobaSi) da TiTqmis mTlianadabsorbirdeba kuW-nawlavis traqtidan, rac dakavSirebuliapreparatis SemadgenlobaSi kofeinis arsebobiT.6 mg alfa-dihidroergokriptinis peroralurad miRebis Semdegmisi C max Seadgens 25pg/ml.dihidrirebuli Wvavis rqis alkaloidebi mcire raodenobiTgadadis dedis rZeSi.alfa-dihidroergokriptinis T ½ Seadgens ara umetes 2 sT-s. igiZiriTadaT gamoiyofa naRveliT.Cveneba:- cerabrovaskuluri ukmarisoba (cerebruli aTerosklerozisSedegad);- Tavis tvinSi sisxlmimoqcevis darRvevis Semdgomi narCenimovlenebi;- gonebrivi aqtivobis daqveiTeba, mexsierebis gauareseba,yuradRebis koncentraciis daqveiTeba, orientaciis darRveva;- Sakikis profilaqtika;- iSemiuri genezis koxleo-vestibuluri darRveva(Tavbrusxveva, yurebSi Suili, hipoakuzia);- menieris davadeba;- retinopaTia (nawilobriv diabeturi da hipertonuli);- periferiuli arteriuli sisxlmimoqcevis darRveva (kerZod,reinos daavadeba da sindromi);- venebis qronikuli ukmarisoba.miRebis wesi da dozireba:niSnaven 1-2 tabletis odenobiT 2-jer dReRameSi. preparatigamoiyeneba sakvebis miRebisas, mcireodeni siTxis miyolebiT.gverdiTi movlenebi:gul-sisxlZarRvTa sistemebis mxriv: arteriuli wnevisdaqveiTeba, taqikardia.saWmlis momnelebeli sistemis mxriv: iSviaTad – gulisreva,epigastralur midamoSi tkivilis SegrZneba.alergiuli reaqciebis mxriv: kanis qavili, gamonayari.

winaaRmdegCveneba:preparatis SemadgenlobaSi Semavali komponentebis mimarTindividuluri mgrZnobeloba.orsulobisa da laqtaciis periodi:orsulebSi vazobralis gamoyenebis usafrTxoeba ar arisdadgenili.laqtaciis periodSi vazobralis gamoyenebam SesaZlebeliagamoiwvios laqtaciis Semcireba.gansakuTrebuli miTiTebani:arteriuli hipertoniiT Sepyrobil pacientebSi vazobralisdaniSvnisas ar aris gamoricxuli antihipertenziulipreparatebis gamoyenebis aucilebloba.urTierTqmedeba sxva samkurnalo saSualebebTan:vazobralisa da antihipertenziuli preparatebis erTdrouligamoyenebisas SesaZlebelia arteriuli hipotenziisa da guliswasvla.Warbi dozireba:ar aRiniSneba.vargisianobis vada:5 weli. SefuTvaze aRniSnuli vadis gasvlis Semdeg preparatisgamoyeneba ar aris rekomendebuli.Senaxvis pirobebi:inaxeba nestisagan bavSvebisagan dacul adgilas oTaxistemperaturaze.SefuTva:tabletebi SefuTvaSi.mwarmoebeli:“Chiesi S.A.” (France)

farmakologiuri komitetisTavmjdomaren. gongaZe