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Universiteit van die Oranje-Vrystaat - SAMJ Archive Browser

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26 VOL 80.7 DEC 1991<br />

<strong>SAMJ</strong><br />

Protein content of amniotic fluid - pitfalls in research planning<br />

To the Editor: A simple urine 'dipstick"can be used to<br />

distinguish amniotic fluid from urine,' and we therefore<br />

decided to determine whether 'dipsticks' could be used to<br />

c o b rupture of membranes.<br />

To validate the method, we first carried out estimations<br />

of protein content and comparative dipstick values on 48<br />

specimens of liquor arnnii obtained f+om third-trimester<br />

amniocentesis.<br />

To our encouragement, we found that dipsticks always<br />

tested positive for protein in liquor and that there was some<br />

correlation with the amount of protein present, in that the<br />

mean values were + = 261 mp/dl (N = 8), ++ = 386 mg/d<br />

(N = 34) and +++ = 775 mg/d (N = 6).<br />

Armed with this 'valuable' information we then proceeded<br />

to test vaginal 'fluids' before and after rupturing<br />

. -<br />

Aan <strong>die</strong> Redaktem Ek verwys na <strong>die</strong> brief <strong>van</strong> dr. Burger'<br />

waarin gestel word dat: 'dit herhaaldelik bewys is dat akah01<br />

<strong>die</strong> vernaamste oorsaaklike faktor in motorongelukke en'<br />

aanrandings is'.<br />

. ,,<br />

. -<br />

& -<br />

Daar bestaan geen navorsing wat aantoon dat alkohol<br />

<strong>die</strong> vemaamste oorsmklike fakm by motorongelukke is nie.<br />

Die enigste navorsing wat <strong>die</strong> afgelope paar jaar in Suid-<br />

Afiika dew <strong>die</strong> Nasionale Instirnut vir Verkeer en Pad-<br />

, ; navorsing gedoen is, het aangetoon dat alkohol verantwoordelik<br />

is vir slegs 3,2% <strong>van</strong> alle ongelukke. Ek is seker<br />

daar<strong>van</strong> dat dr. Burger geen inligting het om sy stelling te<br />

L<br />

.<br />

-<br />

1 -<br />

t<br />

,-*<br />

,-<br />

tt<br />

? I t<br />

5, staaf nie en ek sou graag <strong>van</strong> hom vemeem in<strong>die</strong>n <strong>die</strong> teen-<br />

1<br />

deel waar is.<br />

, Dit is we1 so dat produkte wat alkohol bevat, ongelukkig<br />

* misbruik word deur minderhede, meestal met ernstige<br />

' gevolge vir almal betrokke. So ook kan haseutiese mid-<br />

dels wat vryelik beskikbaar is en geadverteer word, misbruik<br />

~mer~en& treatment of Jehovah's Witnesses<br />

? .<br />

To the Editor: The 'Opinion' by Burrows et al.' calls for a<br />

Berent perspective. Thankfully numerous doctors in both<br />

, I . ~ the private and the public sectors treat Jehovah's Wimesses<br />

. in accordance with their wishes. They are usually not in<br />

sympathy with, or do not even comprehend, the reasons for<br />

the patient's re- of blood; nevertheless their ethics dic-<br />

, i tate that the doctor is there for the patient and not vice<br />

, . versa. Their respect for the fundamental ethic of informed<br />

consent or refusal of consent is to be applauded. It is within<br />

the legal right of a doctor to refuse to take on 2 case. Yet it<br />

I speaks volumes about his basic humanity when he accom-<br />

1. . modates a patient in dire need and, despite the frustration<br />

h .<br />

6<br />

he may feel at the limitation imposed on therapeutic<br />

options, tries all else in accord with the best standards<br />

, he knows. It also speaks of his basic humility and open-<br />

mindedness when he is prepared to use forms of therapy,<br />

hitherto untried by himself, that others with more experi-<br />

.> 3 i ence in dealing with the acutely anaemic Jehovah's Wimess<br />

V L, ,<br />

, b, .-fq -1 - find helpful. To claim that informed refusal of consent for a<br />

particular aspect of proffered treatment with suggestions of<br />

alternatives is a 'call for mismanagement' with which the<br />

< a - '-*-I & J doctor refuses to taint his ethics may well be- a thin veil for<br />

.. . a .. ,.. . ,<br />

intellectual arrogance and bigotry.<br />

, P.<br />

L- . The contention that the cases of survival with extremely<br />

,<br />

membranes. To our editication and dismay we found d<br />

all 28 vaginal tests were positive before (+ = 8, ++ =<br />

+++ = 8) and after rupture of membranes (+ = 0, ++ =<br />

+++ = 17).<br />

Urine 'dipsticks' are therefore of no value in c 0 6<br />

rupture of membranes, and we would have saved om:l<br />

a great deal of time and laboratory work had we perfonr<br />

the second part of the study initially.<br />

J. DOMMISSE<br />

Depamnent of Obstemn and Gynaecology<br />

University of Cape Town<br />

- -<br />

1. Walsberg R, McCulloch J. it &e or amniotic fluid? S Aj. I<br />

J 1985; 68: 918.<br />

word deur minderhede. Dit is wensdenkery om te betc<br />

dat <strong>die</strong> staak <strong>van</strong> advertensies <strong>van</strong> produkte wat alkol<br />

bevat tot gevolg sal h2 dat <strong>die</strong> 'wonderlike dag' aantrt<br />

wanner daar nie meer misbruik is nie. Die reg tot vrye t,<br />

gang <strong>van</strong> en matige gebruik deur <strong>die</strong> bree bevolking beho<br />

nie ingeperk te word omdat minderhede 'n produk rr<br />

bruik nie. 'n Baie meer produktiewe en realistiese opm<br />

sou wees om te konsentreer op <strong>die</strong> opvoeding var. I<br />

minderhede wat hier<strong>die</strong> produkte misbruik sodat hien<br />

wangedrag gestaak word. ;<br />

1. Burger MS. Alkoholadvertensies (Brief). S Afr Med J 199 1;<br />

108.<br />

low haemoglobin levels with which 'medical publicauc<br />

are dotted' can be discarded 'precisely because they 2<br />

unusual' seems failacious. They are 'unusual' for at le,<br />

four reasons that do not allow their findings to be inv&<br />

ted. Firstly, very few, if any, non-Jehovah's Wimess patlel<br />

will be allowed to remain untransfused at extremel: I(<br />

haemoglobin values. (Besides, we all know of numero<br />

transfused patients who have not survived either.) 3<br />

leaves the Jehovah's Wimess in dire straits; not only n<br />

there relatively few of them around, but acutely axen<br />

ones are even rarer. The third factor is that many of h<br />

acutely anaemic Witnesses are either clandestinely L%<br />

fused by overzealous 'good Samaritans' or abandond<br />

truly suboptimal marmgement, making death inevi-ab<br />

Fourthly, not even a moderate percentage of cases o2 sl<br />

vival are published. In many centres which kquentlj trl<br />

Jehovah's Wimesses in accord with their wishes, these sl<br />

vivals have become routine and thus no longer newswcd<br />

Others simply do not have the time or interest TO<br />

through the rigours of publishing.<br />

In effect, Burrows et al. are putting the desp-rz<br />

Jehovah's Wimess into a no-win situation. He eithe:<br />

lates his deeply held religious convictions or he gets ro,<br />

merely token, treatment, since the alternative methods 2

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