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Q koorts - SWAB

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S. aureus<br />

log CFU/mg prot. from time 0<br />

Farmacodynamie van antibiotica<br />

2<br />

0<br />

oxacillin<br />

E min<br />

-2<br />

-4<br />

E max<br />

-2 -1 0 1 2<br />

2<br />

0<br />

gentamicin<br />

E min<br />

-2<br />

-4<br />

-2 -1 0 1 2<br />

log extracellular<br />

concentration (X MIC)<br />

E max<br />

Barcia-Macay et al. Antimicrob. Agents Chemother. 2006; 50(3):841-51<br />

17-06-2010 Therapeutic Drug Monitoring: A pharmacodynamic approach (<strong>SWAB</strong>, Utrecht) 227

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