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Q koorts - SWAB

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Enkele sleutels tot succes (vervolg…)...<br />

Nee<br />

Succes ?<br />

Ja<br />

Stel herbeoordeling voor<br />

• dosering<br />

• therapeutische schema<br />

• antibiotica klasse<br />

op PK/PD eigenschappen<br />

Overweeg<br />

"step-down" therapie<br />

(indien uit microbiologish<br />

standpunt<br />

aanvaardbaar)<br />

Help clinici om aanbevelingen<br />

baseren op<br />

(i) lokale epidemiologie,<br />

(ii) kennis van PK/PD, en<br />

(iii) risico op resistentie<br />

17-06-2010 Therapeutic Drug Monitoring: A pharmacodynamic approach (<strong>SWAB</strong>, Utrecht) 272

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