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H$aVm h¡ Omo grE 1 Am¡a grE 3 H$m hmo Am¡a BgHo$ d`ñH$ Myho na<br />
{hnmoH¢$nb {nam{_S>b Ý`yamÝg H$m n[aUm_ h¡ & Bgr àH$ma {hnmoH¢$ng<br />
_| hmBnmo~o[aH$ {hnmopŠg`m VWm ßbmpñQ>{gQ>r H$m X¡{hH$ {XImdo H$m<br />
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_m\$m©bm°{OH$b _aå_V AmMaU H$s j{V go gh-g§~§Y aIVm ho &<br />
AV: H«$m°{ZH$ hmB©nmopŠg`m _m\$m©bmOr H$mo _aå_V Ho$ gmW grI<br />
Am¡a ñ_¥{V na Aga H$aVm h¡ & AmJo Bg AÜ``Z H$m CÔoí`<br />
O¡dagm`{ZH$ VWm d¡ÚwV^m¡{VH$s` ~Xbmdm| na hmBnmopŠg`m Ho$<br />
à^md H$s OmZH$mar hm{gb H$aZm h¡ & EM ~r EM Ho$ S>o{bQ>o[a`g<br />
à^mdm| H$mo ñZm`w{dH$ AmYma na g_PboZm hmB©AmëQ>rQ²>`yS><br />
hmBnmopŠg`m à^m{dV {dH$mam| Ho$ CnMma _| {M{H$ËgH$s` `moOZmAm|<br />
Ho$ {dH$mg H$m H$maU ~Z OmVm h¡ &<br />
~ogmoboQ>ab A{_½S>mbm (~r Eb E) H$mo emídV ê$n _| A{H«`mË_H$<br />
~Zm XoVo h¢ Zht Vmo B§Q²´>m-A{_½S>mbma B§OoŠeZ XoH$a Vm{ËdH$ ê$n<br />
_| A{H«$`mË_H$ ~Zm XoVo h¢ & {hnmoH¢$ng, AJ«Jm_r H$m°aQ>oŠg VWm<br />
goßQ>_ _| {gQ>mBbH$mo{bZpñQ>amBO (E gr EM B©) Xm~ H$mo JUZr`<br />
ê$n _| H$_ H$a XoVm h¡ & gmW hr A{_½S>mbm H$m A{H«$`mË_H$ ~Zm<br />
XoZm E gr EM B© H$m`©H$bmn Ho$ ñVa _| Xm~mpÝd{V H$_r H$mo CbQ>m<br />
H$a XoVm h¡ & Xm~ {hnmoH¢$ng _| go[aQ>mo{Z`Z, S>monm_mBZ,<br />
ZmoarnmBZ\«$mBZ Ho$ ñVa H$mo ~hþ_hËdnyU© ê$n go H$_ H$a XoVm h¡ &<br />
Cgr ê$n _| ½byQ>m_oQ> Ho$ ñVa H$mo ~T>m XoVm h¡ & _Ja A{_½S>mbm Ho$<br />
A{H«$`mË_H$ ~Zm XoZo go Xm~mpÝdV Ord{H«$`mË_H$ E_mBÝg CbQ><br />
OmVo h¢ & h_Zo Am¡a ^r BZHo$ à{V _yë`m§H$Z Omar aIm h¡ & X~md _|<br />
AmMaU Am¡a _m\$m©bmo{OH$b ñVam| _| E{_½S>mbmo - {hnmoH¢$nb A§V:<br />
{H«$`mE± Omar h¢ &<br />
H«$mo{ZH$ EŠgnmoOa Qy> hmBnmo~m[aH$ hmBnmpŠg`m àmoSw>gog S>oZS´>mB{Q>H$ EQ´>mo\$s Am°\$<br />
hmBnmoH$månb CA3 {nam{_S>b Ý`yamÝg Ÿ& (E) ~«m§_MtJ nm§Q>g H$s Hy$b g§»`m<br />
Xe{Vm h¡ Am¡a (~r) S>oZS´>mB{Q>H$ H$s bå~mB© Xe{Vm h¡ &<br />
_mS²>`yboeZ Am°\$ ñQ²´>og BÝS²>`yñS> {hnmoH¢$nb {S>ñ\§$ŠeÝg _|<br />
A{_½S>mbm H$m nmÌ (S>m°. ~r.Eg. e§H$aZmam`U amd, S>m°. Q>r.Ama.<br />
amOy : àm`moOH$ : S>m°. gw_V MQ>Ou, O¡d{dkmZm| H$m amï²´>r` Ho$ÝÐ,<br />
~|Jbya)<br />
X¡{hH$ X~md grI Am¡a ñ_¥{V {dhrZVm Am¡a H$moboZ{O©H$b<br />
{S>ñ\§$ŠeZ Ho$ gmW {S>OZaoQ>rd ~Xbmd Ho$ gmW gh g§~§Y aIZm h¡<br />
& h_mao nyd© AÜ``Zm| go `h ñßîQ> ê$n go àX{e©V hþAm h¡ {H$<br />
{hnmoH¢$ng _| Xm~nyU© {S>OZaoQ>rd ~Xbmd Omo S>|S²´>r{Q>H$ E\²«$mo\$s g{hV<br />
h¡ `h EgrEMB© H$m`©H$bmn Am¡a {d{eï> ñ_¥{V j{V Am¡a H$_r<br />
½byQ>_oQ> EŠg¡Q>mopŠgQ>r Ho$ H$maU hmoVr h¡ & VWmnr, Myho Ho$ _pñVîH$<br />
Ho$ {d{^Þ ^mJm|§ Ho$ {d{^Þ ñZm`w{dH$ ñVa Ho$ narjU go `h àmá<br />
H$a {b`m h¡ {H$ E_mo½S>mbS> Am¡a {hnmoH¢$ng Ho$ X~md à{V{H«$`m H$m<br />
narjU H$moQ>uH$b Ed§ H$moboZ{O©H$ àUmbr Ho$ à^md go hmoVr h¡ &<br />
X¡{hH$ X~md ~r Eb E nram{_S>mb Ý`yamÝg Am\$ X A{_½Xmbm _|<br />
S>|S²´>rH$ hmBnaQ²´>m°\$s H$m H$maU ~ZVm h¡ & amgm`{ZH$ g§nH©$`wº$<br />
Am`~moQ>o{ZH$ E{gS> H$m à`moJ H$aHo$ VZmd `m Xm~ Ho$ g_`<br />
ñQ´>g {S>{H«$Og X E{gQ>bH$mobmBZñSQ´>og (AChE) EŠQ>rdoQ>r BZ X hmBnmoH$m_ng<br />
EÊS> \«§$Q>b H$mQ}Šg Ÿ& ~mBboQ´>b bogÝg Am°\$ ~mgmoboQ´>b E{_½S>mbm H$ånboQ>br<br />
[adg}g X ñQ´>g-B§Sy>ñS> {S>{H«$g BZ AChE EŠQ>rdoQ>r BZ ~moV [aOÝg Ÿ& S>oQ>m BO<br />
EŠgàñS> EO _rZ ± SEM, *pmob, $$ p< 0.0001 vs ñQ´>g<br />
d`ñH$ _pñVîH$ _| ñZm`w{dH$sOoZo{gg : B§ßbrHo$eZ \$ma ñQ>¡g B§S²>`yñS><br />
nbmpñQ>{gQ>r BZ X a¡Q> {hnmoH¢$ng (S>m°. ~r.Eg. e§H$aZmam`U amd,<br />
S>m°. Q>r.Ama. amOy)<br />
{hnmoH¢$ng _| d`ñH$ Ý`yamo{OZo{gg grIZo Ho$ {bE ~hþV hr<br />
Amdí`H$ h¡ Am¡a E§Q>r{S>àog|Q>m| Ho$ Z¡Xm{ZH$ H$ma©dmB© Ho$ _mÚ{_H$<br />
~Zm XoZo H$s gmoM h¡ & AmJo `h H$B© noWmbmo{OH$b pñW{V _| _mS²>`yboQ><br />
{H$`m J`m h¡, O¡go Xm~ & B§noaS> Ý`yamo{OZo{gg Ho$ à^m{dV {dH$mam|<br />
_| H$m½ZrQ>rd B§noa_|Q²>g EQ²´>rã`yQ>o~b h¡ & h_mao Adm©MrZ AÜ``Zm|<br />
Zo `h gy{MV H$a {XE h¢ {H$ B§Q²´>mH$«o{Z`b goë\$ pñQ>_yboeZ, Xm~nyU©<br />
j{V`m| _| E_r{b`moaoQ>rd hoVw g§àmá dmVmdaU Am¡a Am¡fYr`<br />
_¡ZrnwboeZ H$mo ~T>mdm XoVm h¡ & Bg AÜ``Z _| h_Zo Xm~ny[aV<br />
j{V`m| _| ñZm`w{dH$ OoZr{gg Ho$ à{V{H«$`mË_H$ nmÌ H$m AÜ``Z<br />
{H$`m h¡ & h_ {hnmoH¢$nb gob àmobrnaoeZ H$m BñVo_mb H$aVo hþE ~r<br />
Ama S>r `y Bå`yZmo{hñQ²´>moHo${_ñQ²´>r Am¡a gob {d^mOZm| H$m AÜ``Z<br />
H$a aho h¢ & BgHo$ {bE ~r Ama S>r `y H$m Ý`yamZm| Am¡a p½b`ñnogr{\$H$<br />
_mH©$g© Ho$ gmW gh-ñWmZrH$aU H$aVo hþE `h Omar h¡ & X~md<br />
{dH$mam| go J«ñV amo{J`m| Ho$ H$m½Zr{Q>d nwZíMoVZ _| AnZo Amn<br />
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