Hindi annual report.pmd - Nimhans

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à^md Ho$ _hËdnyU© _mÜ`_ h¢ &
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g§aMZm Omo KQ>Zm Am¡a VÏ` H$r ñ_¥{V Ho$ {bE hm|, H$m AZwg§YmZ
{H$`m J`m & AV: h_ {hnmoH¢$nb gyMZm à{H« `m na {hßnmoH$s`m Am¡a
AdgmX O¡gr AmMaU naQ>a~oeÝg Ho$ Aga _yë`m§H$Z H$aZo Ho$
{bE Eb Q>r nr VWm Eb Q>r S>r H$m BboŠQ²´>mo {\${O`mbm{OH$b AÜ``Z
H$m à`moJ H$aVo h¢ &
Q>mñH$ _| AÀN>r Vah ~Vm©d H$aZo bJo & {hnmoH¢$ng _|~r S>r EZ E\$
àñVwVrH$aU Zo CZ_| {deof ê$n go ~T>m {X`m & {nam{_S>mb Ý`yamÝg
Ho$ {hnmoH¢$nb H$s JwUmË_H$ {ZarjU Zo d¥{ÕV S>|S²´>r{Q>H$ _m\$m©bmoOr
H$mo {XIm`m S>|S²´>r{Q>H$ _m\$m©bmoOr Ho$ J«mâQ> {Q>í`y H$s nhMmZ H$aZm
^r _wpíH$b H$m H$m_ ~Zm & `h gy{MV H$aVm h¡ {H$ Q²´>mÝgßbm§Q>oeZ
`Úmnr g§nH©$ Am{X _| e_m©Zo H$mo Q²´>mo{\$H$ gnmoQ>© CnbãY H$amVm h¡ &
amob Am°\$ emQ>© Q>_© EZ[aÀS> hmCqgJ BZ _m\$m}bm°{OH$b ßbmpñQ>{gQ>r
BZ ew~rHw$ba bmBgÝS> a¡Q²>g E§S> AmZ ~r S>r EZ E\$ EŠgàoeZ BZ
X {hnmoH¡$§ng (S>m°. {~ÝXw E_. Hw$Å>r)
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g§nH©$ Zo n[aUm_ Kmo{fV {H$`m gmW hr gmW arT> H$s gm§ÐVm H$s
H$_r H$m H$maU ~Z J`m & EZ[aÀS> hmCqgJ H$m AZwgaU H$aVo
S>|S²´>rH$ _m\$m©bmOr H$m gãñQ²>`mZer`b [aH$dar H$m CËnmX H$aVo h¢
Am¡a ñ`y~rŠ`yba g§n{H©$V Myhm| H$s arT> H$s gm§ÐVm {hnmoH|$nb Ý`yamÝg
_| & Cgr àH$ma gm_mÝ` Myhm| g§nÞ ~r S>r EZ E\$ {XImdm ^r ~T>m
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B§Q>oZgr{Q> Am°\$ BDNF EŠgàoeZ BZ X hmBnoH$månb CA3 [aOZ Am°\$ (E) Zm_©b
H§$Q´mob (NC), (~r) EZ[aMS> (EE), (gr) d|Q´>b g~m`Hw$ba {bgÝS> [aES>© BZ
ñQ>§mS>© (VSL+SH), (S>r) d|Q´>b g~m`Hw$ba {bgÝS> a¡Q> Q´>mÝgßbm§Q>oS> {dW Eå~«m`mo{ZH$
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H$Z\$moH$b boga ñH¡$qZJ _mBH«$moñH$mon, ñHo$b ~ma = 150 µm
bm±J Q>_© àmoQ>oZ{eEeZ BZ X hmBnoH$månb gMm\$a H$moboQ´>b n°Wdo (CA1) [X
gMm\$a H$moboQ´>b n°Wdo dmO ñQ>r_yboQ>oS> EÊS> X EPSPs do`a aoH$moS>}S> \$_© X ñQ´>mQ>_
Am°\$ X CA1 n¡am{_S>b Ý`yaÝg Ÿ& (E) emoO X nmoQ>oZmBr`eZ Am°\$ X aoñnmÝg An
Qy> 100 {_ZQ²>g nmoñQ> nmoQ>oZmhr`eZ Ÿ& X BZgoQ> emoO X [aàO|Q>oQ>rd aoH$m{S>ª½g
{~\$moa EÊS> AmâQ>a hmB© {\«$¹o$Ýgr ñQ>r_yboeZ (EME\$Eg)Ÿ& (~r) emoO X EdaoO
nmoQ>oZm{e`eZ \$mbmoqdJ EME\$Eg Ÿ&
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Q²´>mÝñn¡eZ H$s gmYH$Vm (S>m°. q~Xw E_. Hw$Q²>Q>r, S>m°. Q>r. Ama. amOy)
AÜ``Zm| go `h nm[aV hþAm {H$ go~rŠ`yba g§H$n© Ho$ {deof grI
j{V H$s E_r{b`moaoqQ>J _| E§~r`mo{ZH$ {hnmoH¢$nb {Q>í`y H$s gmYH$Vm
H$m AÜ``Z H$aZm & Xmo _hrZo Ho$ Q²´>Ýgßbm§Q>oeZ (B© 18 {hnmoH¢$nb
{Q>í`y) Ho$ níMmV² ñ`y~rŠ`yba g§n{H©$V Myho AmN> hmW ao{S>`b _oP
ñ`y~rŠ`yba Myhm| _| {hnmoH¢$nb gob H$s aoemAm| Ho$ ~Xbmd H$s Or{dV
pñW{V H$s àXe©Zr H$s JB© (S>m°. {~ÝXw E_. Hw$Å>r, S>m°. Q>r. Ama. amOy,
gh`moJ : S>m°. E_ E_ n{ZH$a, ZoeZb g|Q>a \$ma ~m`mobmo{OH$b
gm`Ýg, ~|Jbya)
ñ`y~rŠ`yba g§n{H©$V Myhm| H$s Z_yZm| H$m à`moJ H$aVo hþE , àmW{_H$
AÜ``Z go {hnmoH¢$nb gob aoImE± - EM 3 Am¡a nr40 EM 1 d¡dmo
_|, H$s Or{dVVm H$s àXe©Zr àmßV H$s JB© & {hnmoH¢$nb S>o_oO`wŠV
Myhm| H$s Z_yZo _w»`V`m Omo XrK©H$mb VH$ Or{dV aho do bJ^J N>:
_hrZo _w»` ê$n _| S>|Q>oQ> Jwê$ na S>r Am` àW_ - bo~b EM 3
AWdm nr 40 EM 1 AWdm Or nr E\$ nm°{OQ>rd EM 3 gob aoemE±
O~ Q²´>mÝgnboQ> {H$`m J`m `m H$mn©g H$mbmog_ AWdm grE1
{hnmoH¢$ng & nhbo `h [anmoQ>© Zht {H$`m J`m Wm &
ñ`y~rŠ`yb_ Am¡a {deof gyMZm à{H«$`m : h_Zo ñ`y~rŠ`yb_, grE 1
{hnmoH¢$ng Am¡a E§Q>moarZb H$m°Q>}Šg Omo {deof grI Ho$ gh`moJ Ho$
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