الانزيمات-1
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Lipoic acid<br />
حمض دهنى مشبع ذو 8 ذراؤ كربول<br />
كربول 6و7و 8مكونة حلقة غير متجانسة بذرتال كبريؤ.<br />
يعمل كمجمواة تعويضيةgroup prosthetic النزيماؤ<br />
:نقل الهيدروجيل ومجمواة<br />
.<br />
acyl group<br />
• Covalently attached to Apo enzyme – binds<br />
an amide bond to ε-amino group of lysine,<br />
why it is also called lipoamid.<br />
•<br />
•<br />
•<br />
• Oxidation and decarboxylatio of a-ketoacids<br />
(pyruvate dehydrogenase, a-ketoglutarate<br />
dehydrogenase).<br />
• Antioxidant (reduced form is regenerated vit.<br />
C and vit. E).
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