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Difference between the coenzyme and<br />

prosthetic group<br />

• Coenzyme act as second substrate the enzyme<br />

reaction is completed coenzyme is transferred<br />

to another apoenzyme it regenerates when<br />

reacts with another substrate (coupled reaction).<br />

• Prosthetic group covalently bound to the enzyme<br />

regenerates in succession with two different<br />

substrates.

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