BPSD und herausforderndes Verhalten ... - Alzheimer Europe
BPSD und herausforderndes Verhalten ... - Alzheimer Europe
BPSD und herausforderndes Verhalten ... - Alzheimer Europe
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Differential Risk of Death in Older Residents in Nursing Homes<br />
Prescribed Specific Antipsychotic Drugs<br />
Huybrechts KF et al, BMJ 2012, Feb 23 e-pub.<br />
• Cohort study in 45 US nursing homes; 2001 – 2005<br />
• 75445 new users of antipsychotics: haloperidol,<br />
aripiprazole, olanzapine, quetiapine, risperidone,<br />
ziprasidone<br />
• Increased risk of mortality following antipsychotics<br />
• Dose-response relationsship for all APs except<br />
quetiapine<br />
• Compared with risperidone, users of haloperidol had<br />
an increased risk of mortality and users of quetiapine<br />
a decreased risk; this was true for all causes of death<br />
investigated; other drugs in-between
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