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Monday<br />
March 4 Oral Sessions<br />
Session 17 CROI <strong>2013</strong><br />
e Monday, 4-6 pm; B406<br />
Session 17–Symposium<br />
Is Something Bugging You?<br />
Conveners:<br />
Giulia Marchetti, San Paolo Hosp,<br />
Univ of Milan, Italy<br />
John Zaunders, St Vincent’s Hosp,<br />
Sydney, Australia<br />
51<br />
The Human Microbiome in Health and<br />
Immunodeficient States<br />
Frederic Bushman*, G Wu, J Lewis, H Li, K Bittinger,<br />
E Charlson, C Hoffmann, and R Collman<br />
Univ of Pennsylvania Perleman Sch of Med, Philadelphia, US<br />
52<br />
HIV and SIV Pathogenesis at the Interface of<br />
Gut Mucosal Immune Defense and Microbiota<br />
I Grishina, L Hirao, L Nagy, S Sankaran, A Baumler, M Marco,<br />
H Cheng, and Satya Dandekar*<br />
Univ of California, Davis, US<br />
53<br />
Treating Microbial Translocation in<br />
Progressive HIV/SIV Infections<br />
N Klatt 1 , Z Klase 1 , M Quinones 2 , D Hazuda 3 , M Miller 4 , J Segre 5 ,<br />
J Lifson 6 , E Haddad 7 , J Estes 6 , and Jason Brenchley* 1<br />
1 Prgm in Barrier Immunity and Repair, NIAID, NIH, Bethesda,<br />
MD, US;; 2 Bioinformatics and Computational Biosci Branch<br />
OCICB, OSMO, OD, NIAID, NIH, Bethesda, MD, US;; 3 Merck<br />
Res Labs, West Point, PA, US;; 4 Gilead Sci, Inc., Foster City, CA,<br />
US;; 5 Genetics and Molecular Microbio Branch, NHGRI, NIH,<br />
Bethesda, MD, US;; 6 ACVP, SAIC-Frederick, Inc, Frederick Natl<br />
Lab for Cancer Res, MD, US;; and 7 Vaccine and Gene Therapy<br />
Inst-Florida, Port St Lucie, US<br />
54<br />
The Enteric Virome in AIDS<br />
S Handley 1 , L Thackray 1 , G Zhao 1 , R Presti 1 , J Brenchley 2 ,<br />
R Veazey 3 , T Stappenbeck 1 , D Wang 1 , D Barouch 4,5 ,<br />
and Herbert Virgin* 1<br />
1 Washington Univ Sch of Med, St Louis, MO, US;; 2 Lab of<br />
Molecular Microbio, NIAID, NIH, Bethesda, MD, US;; 3 Tulane<br />
Natl Primate Res Ctr, Tulane Univ Sch of Med, Covington, LA,<br />
US;; 4 Ctr for Virology and Vaccine Res, Beth Israel Deaconess<br />
Med Ctr, Boston, MA, US;; and 5 Ragon Inst of MGH, MIT, and<br />
Harvard Med Sch, Boston, MA, US<br />
5:30-6 pm<br />
Panel Discussion<br />
Objectives: This session is directed to clinicians and scientists<br />
interested in understanding the roles of the microbiome and the<br />
virome in the pathogenesis of HIV infection and AIDS. Recent<br />
discoveries in these areas will be discussed. It is assumed that<br />
participants are familiar with the general concept of microbiomes<br />
and have some understanding of the molecular mechanisms used<br />
for its investigation. At the completion of the session, participants<br />
will be knowledgeable about the gut and lung microbiomes, the<br />
alterations in the gut virome associated with lentiviral infections,<br />
and their influence in pathogenesis.<br />
8 � 20th Conference on Retroviruses and Opportunistic Infections<br />
e Monday, 4-6 pm; Ballroom 3-4<br />
Session 18–Symposium<br />
Preventing HIV/AIDS in the US: Can We Do Better?<br />
Conveners:<br />
Wayne Duffus, CDC, Atlanta, GA, US<br />
Monica Sweeney, New York City Dept<br />
of Hlth, NY, US<br />
55<br />
Drivers of the HIV Epidemic in the Southern<br />
US<br />
Adaora Adimora<br />
Univ of North Carolina at Chapel Hill, US<br />
56<br />
What Do Sexual Networks Tell Us about How<br />
to Block Transmission?<br />
Steven Goodreau<br />
Univ of Washington, Seattle, US<br />
57<br />
How Should We Spend Our Prevention<br />
Dollars?<br />
Carlos del Rio<br />
Emory Univ Ctr for AIDS Res, Atlanta, GA, US<br />
58<br />
Addressing the Cascade of Care<br />
Alan Greenberg<br />
George Washington Univ and District of Columbia Devt Ctr for<br />
AIDS Res, US<br />
5:30-6 pm<br />
Panel Discussion<br />
Objectives: This session is directed to clinicians and scientists<br />
interested in HIV prevention, treatment, and policy. It is assumed<br />
participants are familiar with basic knowledge of HIV epidemiology<br />
in the US, and HIV prevention and treatment modalities. At the<br />
completion of the session, participants will be knowledgeable about<br />
which populations in the US are not being reached adequately,<br />
factors that may be driving these failures to prevent HIV infection<br />
and diagnose and adequately treat HIV infected persons, and some<br />
proposed solutions for addressing the HIV/AIDS epidemic in the US.