Aus dem Institut für Tierzucht und Vererbungsforschung - Stiftung ...

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Contents Chapter 1 Introduction …………………………………………………………………………………... 1 Chapter 2 Primary cataract - A review ………………………………………………………………….. 5 Chapter 3 Analysis of systematic and genetic effects on the prevalence of primary cataract, persistent pupillary membrane and distichiasis in the two color variants of English Cocker Spaniels ……………………………………………………………………………... 27 Chapter 4 A retrospective study on the prevalence and formation of primary cataract in two pedigrees from the German population of English Cocker Spaniel ……………………. 53 Chapter 5 Genetic evaluation of primary cataracts in the German population of single-colored English Cocker Spaniels ……………………………………………………………………. 71 Chapter 6 Evaluation of canine heat-shock transcription factor 4 (HSF4) as candidate for primary cataract in English Cocker Spaniels and wire-haired Kromfohrlanders ……………………. 91 Chapter 7 Molecular genetic analysis of primary cataracts in single- and multi-colored English Cocker Spaniels and wire-haired Kromfohrlanders ………………………………. 101 Chapter 8 General discussion ………………………………………………………………………… 125 Chapter 9 Summary …………………………………………………………………………………... 133 Chapter 10 Erweiterte Zusammenfassung …..…………………………………………………………. 137
Page 4 and 5: Bibliografische Informationen der D
Page 6 and 7: Wissenschaftliche Betreuung: Prof.
Page 10 and 11: Chapter 11 Appendix ……………
Page 12 and 13: Introduction Introduction Eye disea
Page 14 and 15: Introduction 4
Page 16 and 17: Canine primary cataract - A review
Page 18 and 19: Review of canine primary cataract 2
Page 20 and 21: Review of canine primary cataract c
Page 22 and 23: Review of canine primary cataract t
Page 24 and 25: Review of canine primary cataract B
Page 26 and 27: Review of canine primary cataract G
Page 28 and 29: Review of canine primary cataract O
Page 30 and 31: Table 1 Review of canine primary ca
Page 32 and 33: Table 3 Review of canine primary ca
Page 34 and 35: Table 3 (continued) Review of canin
Page 36 and 37: Table 3 (continued) Review of canin
Page 38 and 39: Genetic analysis of primary catarac
Page 58 and 59:
Genetic analysis of primary catarac
Page 60 and 61:
Page 62 and 63:
Page 64 and 65:
Retrospective study on prevalence a
Page 66 and 67:
Page 68 and 69:
Page 70 and 71:
Page 72 and 73:
Page 74 and 75:
References Retrospective study on p
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Page 78 and 79:
Page 80 and 81:
Page 82 and 83:
Genetic evaluation of primary catar
Page 84 and 85:
Introduction Primary cataracts (CAT
Page 86 and 87:
USA, 2006). In multivariate analyse
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with parents having RBVs for CAT of
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esults, selection for CAT-late cann
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Tab. 1: Means (first line) and rang
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Tab. 3: Prevalences of primary cata
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Tab. 5: Prevalences of late onset p
Page 98 and 99:
Fig. 2: Cumulative percentages of p
Page 101 and 102:
Evaluation of canine HSF4 with here
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Page 105 and 106:
Page 107 and 108:
References Evaluation of canine HSF
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Molecular genetic analysis of prima
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Page 125 and 126:
Table 1 Molecular genetic analysis
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Page 133 and 134:
Page 135 and 136:
General discussion CHAPTER 8 Genera
Page 137 and 138:
General discussion brown with tan a
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General discussion classification o
Page 141 and 142:
General discussion Überreiter, O.,
Page 143 and 144:
Summary CHAPTER 9 Summary 133
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Summary of SAS (Statistical Analysi
Page 147 and 148:
Zusammenfassung CHAPTER 10 Erweiter
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Zusammenfassung unterschieden. Des
Page 151 and 152:
Zusammenfassung Katarakt. Beim mehr
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Zusammenfassung Material und Method
Page 155 and 156:
Zusammenfassung keine signifikanten
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Appendix CHAPTER 11 Appendix I
Page 159 and 160:
Appendix Table 2 Survey of Kromfohr
Page 161 and 162:
Table 3 (continued) Appendix V
Page 163 and 164:
Position of gene (Mb) Appendix Tabl
Page 165 and 166:
Position of gene (Mb) Table 4 (cont
Page 167 and 168:
Page 169 and 170:
Page 171 and 172:
Appendix Figure 1 First pedigree of
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Appendix Figure 3 Pedigree of multi
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Appendix Figure 5 Collective pedigr
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Appendix Figure 7 Pedigrees of subf
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Kits Appendix DNA purification MinE
Page 181 and 182:
TBE-buffer (1x) 100 ml TBE-buffer (
Page 183 and 184:
Appendix XXVII
Page 185 and 186:
List of publications Publications 1
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Acknowledgements CHAPTER 13 Acknowl
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