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annual meeting program - American Society of Clinical Oncology

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1:15 PM - 2:45 PM<br />

CLINICAL SCIENCE SYMPOSIUM<br />

Saturday, June 5, 2010<br />

Targeted Therapy for Neuroendocrine Tumors: Efficacy, Imaging, and Quality<br />

<strong>of</strong> Life<br />

Location: N Hall B1<br />

CME credit: 1.5<br />

Track(s): Gastrointestinal (Noncolorectal) Cancer<br />

David Linehan, MD—Co-Chair<br />

Washington University School <strong>of</strong> Medicine<br />

Colin D. Weekes, MD, PhD—Co-Chair<br />

University <strong>of</strong> Colorado Cancer Center<br />

1:15 PM Updated safety and efficacy results <strong>of</strong> the phase III trial <strong>of</strong> sunitinib (SU)<br />

versus placebo (PBO) for treatment <strong>of</strong> pancreatic neuroendocrine tumors<br />

(NET). (Abstract #4000)<br />

P. Niccoli, J. Raoul, Y. Bang, I. Borbath, C. Lombard-Bohas, J. W. Valle, S. Patyna,<br />

D. Lu, R. C. Chao, E. Raymond<br />

1:30 PM A prospective, multi-institutional phase II study <strong>of</strong> GW786034 (pazopanib)<br />

and depot octreotide (sandostatin LAR) in advanced low-grade<br />

neuroendocrine carcinoma (LGNEC). (Abstract #4001)<br />

A. T. Phan, J. C. Yao, D. R. Fogelman, K. R. Hess, C. S. Ng, S. A. Bullock,<br />

P. Malinowski, E. Regan, M. Kulke<br />

1:45 PM Randomized run-in study <strong>of</strong> bevacizumab (B) and everolimus (E) in low- to<br />

intermediate-grade neuroendocrine tumors (LGNETs) using perfusion CT as<br />

functional biomarker. (Abstract #4002)<br />

J. C. Yao, A. T. Phan, D. Fogleman, C. S. Ng, C. B. Jacobs, C. D. Dagohoy,<br />

C. Leary, K. R. Hess<br />

Discussion<br />

2:00 PM Kjell E. Oberg, MD, PhD (Abstracts #4000–4002)<br />

Uppsala University<br />

2:15 PM Patient-reported outcomes (PROs) in patients (pts) with pancreatic<br />

neuroendocrine tumors (NET) receiving sunitinib (SU) in a phase III trial.<br />

(Abstract #4003)<br />

A. Vinik, Y. Bang, J. Raoul, J. W. Valle, P. Metrakos, D. Hörsch, B. Korytowsky,<br />

R. Mundayat, R. C. Chao, E. Raymond<br />

Discussion<br />

2:30 PM Ian Chau, MD (Abstract #4003)<br />

Royal Marsden Hospital<br />

139<br />

SATURDAY

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