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annual meeting program - American Society of Clinical Oncology

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MONDAY<br />

Monday, June 7, 2010<br />

3:00 PM - 6:00 PM<br />

ORAL ABSTRACT SESSION<br />

Head and Neck Cancer<br />

Location: E354b<br />

CME credit: 3<br />

Track(s): Head and Neck Cancer<br />

Søren M. Bentzen, MD—Co-Chair<br />

University <strong>of</strong> Wisconsin<br />

A. Dimitrios Colevas, MD—Co-Chair<br />

Stanford University<br />

3:00 PM Vandetanib (VAN) in locally advanced or metastatic medullary thyroid cancer<br />

(MTC): A randomized, double-blind phase III trial (ZETA). (Abstract #5503)<br />

S. A. Wells, B. G. Robinson, R. F. Gagel, H. Dralle, J. A. Fagin, M. Santoro,<br />

E. Baudin, J. R. Vasselli, J. Read, M. Schlumberger<br />

3:15 PM Phase II trial <strong>of</strong> sunitinib in medullary thyroid cancer (MTC). (Abstract #5504)<br />

J. A. De Souza, N. Busaidy, A. Zimrin, T. Y. Seiwert, V. M. Villaflor, K. B. Poluru,<br />

P. L. Reddy, J. Nam, E. E. Vokes, E. E. Cohen<br />

3:30 PM Phase II study <strong>of</strong> oral lapatinib, a dual-tyrosine kinase inhibitor, combined with<br />

chemoradiotherapy (CRT) in patients (pts) with locally advanced, unresected<br />

squamous cell carcinoma <strong>of</strong> the head and neck (SCCHN). (Abstract #5505)<br />

K. J. Harrington, A. Berrier, M. Robinson, E. Remenar, M. Housset,<br />

F. Hurtado de Mendoza, N. Compton, M. Lau, P. Legenne, R. Kumar<br />

3:45 PM An open-label, randomized, phase III trial <strong>of</strong> zalutumumab, a human<br />

monoclonal EGF receptor (EGFr) antibody, versus best supportive care, in<br />

patients with noncurable squamous cell carcinoma (SCCHN) <strong>of</strong> the head and<br />

neck who have failed standard platinum-based chemotherapy (ZALUTE).<br />

(Abstract #LBA5506)<br />

J. H. Machiels, S. Subramanian, A. Ruzsa, G. Repassy, I. Lifrenko, A. Flygare, P.<br />

Sorensen, E. Ehrnrooth, O. Baadsgaard, P. M. Clement<br />

Discussion<br />

4:00 PM A. Dimitrios Colevas, MD (Abstracts #5503–LBA5506)<br />

Stanford University<br />

4:15 PM A phase III trial (RTOG 0129) <strong>of</strong> two radiation-cisplatin regimens for head and<br />

neck carcinomas (HNC): Impact <strong>of</strong> radiation and cisplatin intensity on<br />

outcome. (Abstract #5507)<br />

K. Ang, Q. Zhang, R. H. Wheeler, D. I. Rosenthal, F. Nguyen-Tan, H. Kim, C. Lu,<br />

R. S. Axelrod, C. I. Silverman, R. S. Weber<br />

4:30 PM Postoperative accelerated radiotherapy (POPART) versus conventional<br />

postoperative radiotherapy (CPORT) in squamous cell head and neck<br />

cancer: A multicenter prospective randomized study <strong>of</strong> the Dutch Head and<br />

Neck Cooperative Study Group. (Abstract #5508)<br />

J. A. Langendijk, J. H. Kaanders, P. Doornaert, F. R. Burlage, P. L. van den Ende,<br />

S. B. Oei, R. B. Keus, S. Nuyts, C. R. Leemans, C. H. Terhaard, Dutch Head and<br />

Neck Cancer Research Group<br />

Discussion<br />

4:45 PM Søren M. Bentzen, MD (Abstracts #5507–5508)<br />

University <strong>of</strong> Wisconsin<br />

5:00 PM Prognostic significance <strong>of</strong> interleukin-8 (IL-8) and hepatocyte growth factor<br />

(HGF) in patients with head and neck squamous cell carcinoma (HNSCC)<br />

treated with chemoradiation on a phase III trial. (Abstract #5509)<br />

D. Rischin, R. Fisher, K. Oliner, R. J. Young, H. Cao, G. A. McArthur, L. J. Peters,<br />

B. O’Sullivan, Q. Le<br />

410

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