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annual meeting program - American Society of Clinical Oncology

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SUNDAY<br />

Sunday, June 6, 2010<br />

8:00 AM - 12:00 PM<br />

GENERAL POSTER SESSION<br />

Lung Cancer—Metastatic<br />

Location: S Hall A2<br />

Tracks(s): Lung Cancer<br />

Brd. 31A A multicenter phase II randomized study <strong>of</strong> docetaxel (D)/gemcitabine (G)<br />

weekly followed by erlotinib (E) after progression versus erlotinib followed<br />

by docetaxel/gemcitabine after progression in advanced non-small cell lung<br />

cancer (NSCLC) in fit elderly patients selected with a comprehensive<br />

geriatric assessment (CGA): Groupe Français de Pneumocancerologie<br />

(GFPC)*0504 (Abstract #7536)<br />

H. Le Caer, F. Barlesi, R. Corre, H. Jullian, S. Bota, L. Falchero, A. Vergnenegre,<br />

C. Dujon, J. Y. Delhoume, C. Chouaid<br />

Brd. 31B Efficacy and safety <strong>of</strong> PF-00299804 (PF299), an oral, irreversible, pan-human<br />

epidermal growth factor receptor (pan-HER) tyrosine kinase inhibitor (TKI),<br />

as first-line treatment (tx) <strong>of</strong> selected patients (pts) with advanced (adv)<br />

non-small cell lung cancer (NSCLC). (Abstract #7537)<br />

T. Mok, D. R. Spigel, K. Park, M. A. Socinski, S. Y. Tung, D. Kim, G. Borzillo,<br />

H. Zhang, J. P. O’Connell, P. A. Janne<br />

Brd. 31C EGFR and ABCG2 polymorphisms as prognostic and predictive markers in<br />

the NCIC CTG BR.21 trial <strong>of</strong> single-agent erlotinib in advanced non-small cell<br />

lung cancer (NSCLC). (Abstract #7538)<br />

G. Liu, D. Cheng, A. Le Maitre, N. Liu, Z. Chen, L. Seymour, K. Ding,<br />

F. A. Shepherd, M. S. Tsao<br />

Brd. 32A <strong>Clinical</strong> impact <strong>of</strong> amphiregulin expression in EGFR wild-type non-small cell<br />

lung cancer patients treated with EGFR tyrosine kinase inhibitors. (Abstract<br />

#7539)<br />

M. Chang, J. Lee, C. Jung, Y. Park, J. Ahn, K. Park, M. Ahn<br />

Brd. 32B Biomarker analyses from a phase l study <strong>of</strong> pertuzumab combined with<br />

erlotinib in patients (pts) with non-small cell lung cancer (NSCLC).<br />

(Abstract #7540)<br />

E. Felip, M. Ranson, S. Cedres, M. Brewster, V. Mcnally, M. Venturi,<br />

A. Passioukov, G. Ross, D. Galdermans<br />

Brd. 32C Association <strong>of</strong> KRAS and EGFR mutations with survival in patients with<br />

advanced lung adenocarcinoma. (Abstract #7541)<br />

M. L. Johnson, C. Sima, P. K. Paik, Y. Y. Janjigian, W. Pao, M. G. Kris, M. Ladanyi,<br />

G. J. Riely<br />

Brd. 33A EGFR mutation status and survival after diagnosis <strong>of</strong> brain metastasis in<br />

non-small cell lung cancer. (Abstract #7542)<br />

A. F. Eichler, K. T. Kahle, D. L. Wang, V. A. Joshi, J. A. Engelman, L. V. Sequist<br />

Brd. 33B Rates <strong>of</strong> CNS progression in patients with advanced NSCLC harboring<br />

somatic EGFR mutations and treated with gefitinib or erlotinib.<br />

(Abstract #7543)<br />

S. Heon, B. Y. Yeap, G. J. Britt, M. S. Rabin, D. M. Jackman, B. E. Johnson<br />

Brd. 33C Clinicopathologic differences between lung cancer with EGFR gene major<br />

(exon 19 deletions and exon 21 L858R) and other minor mutations.<br />

(Abstract #7544)<br />

Y. Yamane, K. Goto, H. Kenmotsu, Y. Ohe, H. Ohmatsu, S. Niho, K. Yoh, G. Ishii,<br />

K. Nagai, Y. Nishiwaki<br />

Brd. 34A The usefulness <strong>of</strong> 18 f-fluorothymidine (FLT) and 18 F-FDG PET for early<br />

prediction <strong>of</strong> response to erlotinib therapy in patients with advanced nonsmall<br />

cell lung cancer. (Abstract #7545)<br />

C. Choi, K. Shin, D. Lee, S. Oh, J. Kim, D. Moon, C. Suh, J. Ryu, S. Kim<br />

214

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