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annual meeting program - American Society of Clinical Oncology

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MONDAY<br />

Monday, June 7, 2010<br />

9:45 AM - 11:15 AM<br />

CLINICAL SCIENCE SYMPOSIUM<br />

Novel Therapies and Approaches for Management <strong>of</strong> Gynecologic Cancers<br />

Location: E Arie Crown Theater<br />

CME credit: 1.5<br />

Track(s): Gynecologic Cancer<br />

Robert L. Coleman, MD—Co-Chair<br />

University <strong>of</strong> Texas M. D. Anderson Cancer Center<br />

Ronald J. Buckanovich, MD—Co-Chair<br />

University <strong>of</strong> Michigan<br />

9:45 AM Randomized, double-blind, placebo-controlled phase II study <strong>of</strong> AMG 386<br />

combined with weekly paclitaxel in patients (pts) with recurrent ovarian<br />

carcinoma. (Abstract #5000)<br />

B. Y. Karlan, A. M. Oza, V. L. Hansen, G. E. Richardson, D. M. Provencher,<br />

P. Ghatage, M. Tassoudji, D. E. Stepan, D. M. Weinreich, I. B. Vergote<br />

Discussion<br />

10:00 AM George Coukos, MD, PhD (Abstract #5000)<br />

University <strong>of</strong> Pennsylvania, Perelman Center for Advanced Medicine<br />

Anti-angiogenic Options in Ovarian Cancer<br />

10:15 AM Efficacy and safety <strong>of</strong> farletuzumab, a humanized monoclonal antibody to<br />

folate receptor alpha, in platinum-sensitive relapsed ovarian cancer subjects:<br />

Final data from a multicenter phase II study. (Abstract #5001)<br />

A. J. White, R. L. Coleman, D. K. Armstrong, D. Glenn, A. Bicher, D. A. Richards,<br />

A. Schneeweiss, L. J. Old, C. Schweizer, S. Weil<br />

Discussion<br />

10:30 AM Alan Hilary Calvert, MD (Abstract #5001)<br />

Cancer Research Unit<br />

Targeting the Folate Receptor in Ovarian Cancer<br />

10:45 AM Final results <strong>of</strong> a phase II study <strong>of</strong> voreloxin in women with<br />

platinum-resistant ovarian cancer. (Abstract #5002)<br />

H. W. Hirte, W. P. McGuire III, R. P. Edwards, A. Husain, P. Hoskins, J. E. Michels,<br />

U. Matulonis, C. Sexton, J. A. Fox, G. Michelson<br />

Discussion<br />

11:00 AM Hani Gabra, PhD, FRCP (Abstract #5002)<br />

Imperial College, London<br />

Mechanisms <strong>of</strong> Resistance in Ovarian Cancer<br />

352

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