Nitrous Oxide - MCI
Nitrous Oxide - MCI
Nitrous Oxide - MCI
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• N 2 O + O 2 (70/30) vs O 2 + nitrogen (80/20)<br />
– 2050 patients, for at least 2 hours, mean age 55 y.o<br />
• Lower rate of major complications without N 2 O<br />
– Fever, wound infection, pneumonia, atelectasis, N&V<br />
• Lower cost Graham Anesthesiology 2011<br />
• No change stroke or death but ↑MI Leslie Anesth Analg 2011<br />
• Design issues: ? outcome 2° protective effect of ↑O 2
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