Nitrous Oxide - MCI
Nitrous Oxide - MCI
Nitrous Oxide - MCI
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<strong>Nitrous</strong> <strong>Oxide</strong><br />
Lack of Analgesic Potency<br />
• Pilot study (n=41) N 2O with IN fentanyl (1.5 mcg/kg)<br />
– IN fentanyl 14 min (mean) prior to N2O – Mostly x1 dose; 80% orthopaedic procedures<br />
• No serious adverse events<br />
• Vomiting rate higher vs N20 alone<br />
– 20% (95% CI 7% ‐ 31%) vs 6% (95% CI 4% ‐ 7%) p
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