Nitrous Oxide - MCI
Nitrous Oxide - MCI
Nitrous Oxide - MCI
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Problems with <strong>Nitrous</strong> <strong>Oxide</strong><br />
Homocysteine & B 12 Metabolism<br />
• B 12 effect<br />
– Neurological (neuropathy) and haematologic disease (bone marrow<br />
failure) after N2O in patients with low B12 – Case reports, “prolonged” exposure<br />
– Pernicious anaemia<br />
– Resected terminal ileum<br />
– Dietary deficiency /vegan<br />
Baum Ped Anesth 2007<br />
Sanders Anesthesiology 2008