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Nitrous Oxide - MCI

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The History of <strong>Nitrous</strong> <strong>Oxide</strong><br />

• First synthesized Joseph Priestley in 1772<br />

• Psychotropic effects in 1799 –recreational use<br />

• Advertisement in 1844 “Those who inhale the gas once, are<br />

always anxious to inhale the second time….No language can<br />

describe the delightful sensation produced” seen by dentist<br />

Horace Wells –used as dental analgesia<br />

• In use as anaesthetic since (160 years!)…while others have<br />

disappeared (ether, chloroform etc)

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