morphological changes of reversible injury
morphological changes of reversible injury
morphological changes of reversible injury
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MORPHOLOGICAL CHANGES OF REVERSIBLE<br />
INJURY<br />
• Plasma Membrane Alterations.<br />
• Mitochondrial Changes.<br />
• Dilation <strong>of</strong> the ER.<br />
• Nuclear Alterations.<br />
Under light microscope<br />
• CELLULAR SWELLING<br />
• FATTY CHANGE<br />
REVERSIBLE INJURY<br />
CELLULAR SWELLING<br />
• Incapable <strong>of</strong> maintaining ionic and fluid homeostasis.<br />
• Result <strong>of</strong> failure <strong>of</strong> energy-dependent ion pumps in the plasma membrane.<br />
• Occurs in<br />
• hypoxic <strong>injury</strong><br />
• toxic <strong>injury</strong><br />
• metabolic <strong>injury</strong>.<br />
• Manifested by the<br />
• Cytoplasmic lipid vacuoles .<br />
• Seen in<br />
• Hepatocytes<br />
• Myocardial Cells.<br />
FATTY CHANGES
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