Pharmacology of Antiepileptic Drugs
Pharmacology of Antiepileptic Drugs
Pharmacology of Antiepileptic Drugs
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Epilepsy—GABA<br />
Epilepsy GABA<br />
Major inhibitory neurotransmitter in the<br />
CNS<br />
Two types <strong>of</strong> receptors<br />
– GABAA —post-synaptic, specific<br />
recognition sites, CI- channel<br />
– GABAB —presynaptic autoreceptors,<br />
also postsynaptic, mediated by K +<br />
currents