Pharmacology of Antiepileptic Drugs
Pharmacology of Antiepileptic Drugs
Pharmacology of Antiepileptic Drugs
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Regulation <strong>of</strong> Neurotransmitter release<br />
• Several AED have actions that result in the<br />
regulation <strong>of</strong> neurotransmitter release from the<br />
presynaptic terminal, such as lamotrigine, in<br />
addition to their noted action on ion channels or<br />
receptors.<br />
• Levetiracetam appears to have as its primary<br />
action the regulation <strong>of</strong> neurotransmitter release<br />
by binding to the synaptic vesicle protein SV2A: