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Design of Experiments - US Army Conference on Applied Statistics

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A New Optimality Criteri<strong>on</strong><br />

Recently J<strong>on</strong>es and Nachtsheim proposed a new criteri<strong>on</strong> that<br />

addresses this c<strong>on</strong>cern.<br />

Their designs minimize the squared norm <str<strong>on</strong>g>of</str<strong>on</strong>g> the alias matrix<br />

subject to a lower bound c<strong>on</strong>straint <strong>on</strong> the D-efficiency <str<strong>on</strong>g>of</str<strong>on</strong>g> the<br />

design.<br />

Their results are impressive and provide a safer approach to<br />

screening design for novice investigators.

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