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E-value depends on n, m<br />

Example<br />

– For comparing seqA with seqB: S=88<br />

-> E = 0.001<br />

– For comparing seqA with 1000 seqs:<br />

score 88 -> E=1<br />

Important for db searching:<br />

– n – size of query, m - size of db<br />

E=K m n e −S

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