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E-value depends on n, m<br />
Example<br />
– For comparing seqA with seqB: S=88<br />
-> E = 0.001<br />
– For comparing seqA with 1000 seqs:<br />
score 88 -> E=1<br />
Important for db searching:<br />
– n – size of query, m - size of db<br />
E=K m n e −S