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Why does the BLA[S]T work?<br />
Forget the T-similar words, now use only identities<br />
2 sequences, 100 nucleotides each:<br />
– What's the minimal sequence identity for which<br />
there's a string of 3 consecutive identities?<br />
0 identities, 100 mismatches:<br />
67 identities, 33 mismatches:<br />
but if seqs are 50% id, we'll detect it with prob. 99%<br />
28% id -> we'll detect it with prob. 50%<br />
– how is it calculated?<br />
68st<br />
?