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UCB SA - BNP Paribas Fortis

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Some of the former sites of the <strong>UCB</strong> Group are currently subject to remediation and other sites will be<br />

subject to remediation as a consequence of forthcoming legislation. Even though some of the former<br />

sites of the <strong>UCB</strong> Group currently do not raise any environmental concerns, it cannot be excluded that<br />

future investigations will discover contamination and result in remediation obligations for the <strong>UCB</strong><br />

Group.<br />

It is difficult for the <strong>UCB</strong> Group to estimate the future costs of environmental protection and<br />

remediation because of uncertainties associated with the status of regulations and their future<br />

developments. Taking into consideration its experience, currently known facts and its existing<br />

provisions which were made in light of potential remedial obligations, the <strong>UCB</strong> Group believes that the<br />

capital expenditures and remedial actions necessary to comply with environmental regulations will not<br />

have a material adverse effect on its financial position, results of operations or cash flows.<br />

The <strong>UCB</strong> Group believes that it is in substantial compliance with applicable health, safety and<br />

environmental laws and regulations. The <strong>UCB</strong> Group is concerned about the health and safety of its<br />

employees and the protection of the public health and environment. While its compliance to health,<br />

safety and environmental laws and regulations has not adversely affected the competitive position or<br />

business of the <strong>UCB</strong> Group, it cannot predict the impact of possible future regulations. Although the<br />

<strong>UCB</strong> Group has taken measures to conform to the stricter regulations, such as increasing the efficiency<br />

of its internal research and development process in order to reduce the impact of extended testing on<br />

time-to-market, stricter regulatory regimes could delay product development or restrict marketing and<br />

sales.<br />

15. KEY CONTRACTS<br />

(a) License and Distribution Agreements<br />

Astra Zeneca do Brasil Ltd<br />

In September 2009, the <strong>UCB</strong> Group and Astra Zeneca do Brasil Ltd entered into a partnership relating<br />

to the registration and commercialization of Cimzia® in Brazil, which allows Astra Zeneca do Brasil<br />

Ltd to be the exclusive distributor of Cimzia® in Brazil, with <strong>UCB</strong> retaining the right to co-promotion<br />

of Cimzia® and any future line extensions.<br />

Chiesi Farmaceutici S.p.A<br />

In March 2007, <strong>UCB</strong> Pharma S.A. and Chiesi Farmaceutici S.p.A. entered into a license and<br />

distribution agreement for Chiesi’s pMDI product containing beclometasone diproprionate and<br />

formoterol fumarate (most common brand names: Innovair®/Foster®) for the treatment of asthma.<br />

This license is exclusive in Sweden, Denmark, Norway, Finland and Switzerland (including<br />

Lichtenstein), and sole in Belgium, Luxemburg, Greece (including Cyprus) and Turkey. The agreement<br />

will terminate 15 years after the first commercial sale on a country-by-country basis or the last date on<br />

which the sale of the licensed product in the territory would infringe a licensed patent in the territory,<br />

whichever occurs last.<br />

GlaxoSmithKline K.K.<br />

In July 2005, <strong>UCB</strong> Japan Co., Limited and GlaxoSmithKline K.K. entered into an agreement whereby<br />

<strong>UCB</strong> Japan Co., Limited appointed GlaxoSmithKline K.K. as its new co-distributor for Zyrtec® on the<br />

Japanese market. The agreement expires at the later of the end of a ten year term or the end of a eight<br />

A11250830/2.25/23 Oct 2009 82

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