Clinical Practice Guidelines for the management of locally advanced ...

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Index to Clinical practice guidelines for the management of locally advanced and metastatic prostate cancer. abarelix 54 abbreviations 133–134 abiraterone 116 accessibility 110–111 actuarial survival 135 adrenal gland 135 Adverse Drug Reactions Advisory Committee (ADRAC) 54 age 1 alternative medicine 105 anaemia 54, 56, 99, 135 anaesthetics 134, 135 analgesics 99 androgen deprivation therapy (ADT) 48, 135 biochemical relapse 48–49, 115 and bone health 21–23, 79 castration-resistant prostate cancer continuing after hormone refractory 78 second-line hormone manipulations 75–77 combined androgen blockage (CAB) 18, 19, 53–54, 136 and fatigue 19, 20, 55, 99 locally advanced disease 26–27, 115 choice of 17–18 complications 18–21 early versus delayed 16–17 evidence summaries 17, 18, 20, 23, 24, 29, 31 long-term 29, 30–31 node-positive disease 36–37 quality of life (QOL) 23–24 and radiotherapy 29–31, 36–38 recommendations 17, 18, 21, 23, 24, 30, 31, 34 short-term 29–31 toxicity 18–21 metastatic disease 115 choice of 50–51 early versus delayed 52–53 evidence summaries 51, 52, 53, 56, 57, 58 intermittent or continuous 58–59 and non-steroidal anti-androgen 51–52 and quality of life (QOL) 56–57 recommendations 51, 52, 53, 56, 57, 59 single agent versus total androgen blockade 51–52 toxicity 53–56 side effects 18–23, 53–56 androgen withdrawal 76 androgens 135 Andrology Australia 117, 143 anti-androgen therapy 18, 19, 20, 51–52, 55, 56, 57, 135 antidepressant medication 11 anxiety 10–12 asthenia 55 asymptomatic 135 atrial fibrillation 83 audio tapes 5 Auron Misheil Therapy 2003 116 149 Index
Australia New Zealand Clinical Trials Registry 115 Australian Cancer Network (ACN) 117 benign 135 benign prostate enlargement 135 benign prostatic hyperplasia (BPH) 135 beyondBlue 12, 143 bicalutamide 19, 20, 54, 55, 57 bilateral orchidectomy see orchidectomy biochemical relapse androgen deprivation therapy (ADT) 48–49, 115 chemotherapy 115 described 48 dietary interventions 115 docetaxel 115 emerging therapies 115 evidence summaries 49 radiotherapy 115 recommendations 49 biopsy and diagnosis 1 of prostate 132 bisphosphonates 78–79, 115, 135 and bone pain 80–83 evidence summaries 80, 82 hormone-naïve metastatic bone prostate cancer 66 metastatic disease 66 potencies of 79 side effects 82–83 and skeletal related events (SRE) 79–80 see also zoledronic acid blood transfusions 99 bone health 21–23 see also osteoporosis; skeletal related events (SRE) bone metastases 78–79 and anaemia 99 emerging therapies 116 and samarium 153 84 and strontium 89 84 see also skeletal related events (SRE) bone mineral density (BMD) 21–23 bone pain and bisphosphonates 80–83 and radioisotopes 84–85 and radiotherapy 59–61 and samarium 153 84–88 and strontium 89 84–88 bone scans 1, 75, 135 brachytherapy 135 locally advanced disease 27–28 rise in prostate specific antigen (PSA) following 48 breast changes 19, 20, 54, 55, 56 buserelin nasal spray 54 Cancer Council New South Wales, Cancer Epidemiology Research Unit 117 Cancer Councils 3, 143 Cancer: how are you travelling? 12 cancer information services 143 Clinical practice guidelines for the management of locally advanced and metastatic prostate cancer 150
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Clinical Practice Guidelines for th
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4 Biochemical relapse .............
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FOREWORD The management of prostate
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SUMMARY OF CLINICAL PRACTICE RECOMM
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SUMMARY OF RECOMMENDATIONS Chapter
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Chapter Recommendations Grade Refs
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1 INTRODUCTION 1.1 Natural history
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2 PSYCHOSOCIAL CARE The diagnosis a
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2.2 Effect of psychological and cog
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Evidence summary Level References T
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Recommendation Men with advanced pr
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An Australian cross-sectional study
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10. Dunn J, et al. A review of peer
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41. Sharpley CF, Christie DRH. An a
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different treatments from different
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Evidence summary Level References I
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Evidence summary Level References F
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Despite these reservations and the
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For non-metastatic disease there we
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Evidence summary Level References T
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monotherapy for low-to-intermediate
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Evidence summary Level References M
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for surgery, suggesting that surger
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Microscopic fully resected node pos
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All three trials demonstrated impro
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Evidence summary Level References B
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of an international multicentre ran
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45. Melton LJ, III, Alothman KI, Kh
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76. Little DJ, Kuban DA, Levy LB, Z
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105. Thompson IM, Tangen CM, Parade
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4.2 Androgen deprivation therapy (e
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Evidence summary Level References F
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therapy since such studies would be
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apparent in trials comparing CAB wi
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QLQ instrument published by Cleary
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Note: Larger well-powered studies h
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Eight trials examined acute toxicit
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half of patients experienced pain r
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olus) in addition to radiotherapy a
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References 1. Seidenfeld J, Samson
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Cooperative Group. Scandinavian Jou
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Oncology Group, TROG 96.05). Radiot
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trial. European Journal of Cancer 1
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6 CASTRATION-RESISTANT PROSTATE CAN
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the median overall survival for pat
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There are two points regarding bisp
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with bone pain at study entry. At n
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Recently, there have been reports o
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of these studies 56, 58 and in the
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Side effects (toxicity) As these ra
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hydrocortisone respectively. Tannoc
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5. Manikandan R, Srirangam SJ, Pear
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33. Elomaa I, Kylmala T, Tammela T
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60. Janknegt RA, Abbou CC, Bartolet
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physiotherapists, occupational ther
Page 118 and 119: 7.5 Q2: Symptom control There was e
Page 120 and 121: Informal or family caregivers deriv
Page 122 and 123: 8. Hughes SL, Weaver FM, Giobbie-Hu
Page 124 and 125: 8 COMPLEMENTARY AND ALTERNATIVE (UN
Page 126 and 127: corresponding benefit in obstructiv
Page 128 and 129: 3. Eisenberg DM, Kessler RC, Van Ro
Page 130 and 131: areas of the state were more likely
Page 132 and 133: 8 Miller DC, Litwin MS, Bergman J,
Page 134 and 135: 10 EMERGING THERAPIES It is impossi
Page 136 and 137: APPENDIX 1 GUIDELINE DEVELOPMENT PR
Page 138 and 139: study type. Studies published befor
Page 140 and 141: Grade of recommendation Description
Page 142 and 143: 2. National Health and Research Cou
Page 144 and 145: Dr Carole Pinnock AM Principal rese
Page 146 and 147: Surgery Professor Villis Marshall A
Page 148 and 149: APPENDIX 3 TNM CLASSIFICATION OF PR
Page 150 and 151: Summary Prostate T1 T2 T3 T4 N1 M1a
Page 152 and 153: APPENDIX 4 ABBREVIATIONS AND GLOSSA
Page 154 and 155: Glossary Actuarial survival A metho
Page 156 and 157: Effectiveness The extent to which a
Page 158 and 159: Lymph nodes Small, generally pea-si
Page 160 and 161: Each stage is divided into subgroup
Page 162 and 163: APPENDIX 6 - ORGANISATIONS WHICH PR
Page 164 and 165: Consultant Urologist, Royal Brisban
Page 166 and 167: No conflict of interest to declare.
Page 170 and 171: cardiovascular mortality 19, 54, 55
Page 172 and 173: androgen deprivation therapy (ADT)
Page 174 and 175: and surgery 32-34 survival 18 toxic
Page 176 and 177: and chemotherapy 89-90 see also bon
Page 178 and 179: spinal cord compression 62-63 see a
Page 180 and 181: systemic 141 Tasmania Association f
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