B12 METABOLISM IN HUMANS By NICOLE AURORA LEAL A ...
B12 METABOLISM IN HUMANS By NICOLE AURORA LEAL A ...
B12 METABOLISM IN HUMANS By NICOLE AURORA LEAL A ...
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84<br />
Table 3-2. Use of alternative nucleotide donors by the human ATR<br />
Nucleotide Donor<br />
Activity %<br />
a<br />
ATR 239K ATR 239M<br />
ATP (adenosine-5’-triphosphate) 100 100<br />
ADP (adenosine-5’-diphosphate) ND b ND<br />
AMP (adenosine-5’-monophosphate) ND ND<br />
CTP (cytidine-5’-triphosphate) 9 6<br />
GTP (guanosine-5’-triphosphate) 16 4<br />
UTP (uridine-5’-triphosphate) 8 6<br />
a<br />
ATP is the physiological substrate for the ATR and activity with this nucleotide was set<br />
to 100%.<br />
b ND, none detected