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Utility of the peripheral smear and laboratory studies in the ...

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Approach to <strong>the</strong> PBS<br />

Slide should be well prepared <strong>and</strong> well sta<strong>in</strong>ed<br />

Go to <strong>the</strong> fea<strong>the</strong>red edge –<br />

<br />

<br />

<br />

<strong>the</strong> “Goldilocks”<br />

Red cells aren’t too th<strong>in</strong> (all look like spherocytes)<br />

Red cells aren’t too thick (all look like agglut<strong>in</strong>ation &<br />

Red cells are just right –<br />

approach<br />

well spaced, good central pallor<br />

Note: it is hard to f<strong>in</strong>d <strong>the</strong> “sweet spot”<br />

<strong>smear</strong>s due to high Hct<br />

<strong>in</strong> newborn<br />

rouleaux)<br />

Too th<strong>in</strong> Too thick Just right

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