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Utility of the peripheral smear and laboratory studies in the ...

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Blasts vs<br />

<br />

<br />

<br />

<br />

“Kiddie”<br />

lymphs<br />

This can be hard<br />

Blasts have higher N/C ratios & very f<strong>in</strong>e, powdery,<br />

dispersed chromat<strong>in</strong> +/nucleoli <br />

“little balls <strong>of</strong> nucleus”<br />

Cl<strong>in</strong>ical context is helpful –<br />

beg<strong>in</strong> with?<br />

Look at <strong>the</strong> forest<br />

<br />

<br />

<br />

how suspicious are you to<br />

Monotony – déjà vu - all <strong>the</strong> same p<strong>in</strong>e tree<br />

Heterogeneity – mix <strong>of</strong> p<strong>in</strong>e, fir, spruce (all evergreens, but<br />

<strong>the</strong>y all look a bit different)<br />

Gresik’s rule – look at <strong>the</strong> company <strong>the</strong>y keep!<br />

“Private school” vs “public school”

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