PNH and Thrombosis - Aplastic Anemia & MDS International ...

Coumadin Doses
Typically require adjustment when:
--starting new drugs
-- especially antibiotics
--change in diet
-- feeling unwell
-- most patients will need blood work 3x per week
when first starting coumadin
-- eventually down to once every 3 weeks
Coumadin takes days to work, changes in doses
on a Monday may not affect the INR until
Wednesday. Takes days for the effect to wear
off.