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PNH and Thrombosis - Aplastic Anemia & MDS International ...

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Recommendations regarding Eculizumab<br />

(Soliris) <strong>and</strong> anticoagulation<br />

When considering whether Eculizumab or Anticoagulation is<br />

more appropriate for preventing clots, consider that the risk of<br />

bleeding on anticoagulation (about 1% per year) is similar to the<br />

risk of meningococcal infection in patients on Soliris. However,<br />

for individual patients, one may be of greater concern than the<br />

other.

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