Effectiveness of Laxatives in the Elderly - NIHR Health Technology ...
Effectiveness of Laxatives in the Elderly - NIHR Health Technology ...
Effectiveness of Laxatives in the Elderly - NIHR Health Technology ...
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2<br />
Epidemiology <strong>of</strong> constipation <strong>in</strong> <strong>the</strong> general adult population<br />
TABLE 1 Prevalence <strong>of</strong> constipation <strong>in</strong> adults <strong>in</strong> <strong>the</strong> general population: UK surveys<br />
Authors Sample (age) Symptoms Prevalence<br />
(95% confidence <strong>in</strong>terval (CI))<br />
General population<br />
Connell et al, 1965 Factory workers 1. Frequency (≤ 4 1. 5.1% (4–6)<br />
n = 1055 bowel movements 2. 4% (3–5)<br />
per week)<br />
2. Self-reported<br />
constipation<br />
Thompson & Heaton, 1980 <strong>Health</strong>y adults; Often stra<strong>in</strong><strong>in</strong>g 10% (7–13)<br />
17–91 years at stool<br />
n = 301 (> 1/4 occasions)<br />
Heaton & Cripps, 1993; General population; 1. Frequent stra<strong>in</strong><strong>in</strong>g 1. Men: 39% (36–42);<br />
Heaton et al, 1993 834 men (> 1/4 occasions) women: 51.5% (48–54)<br />
(40–60 years); 2. Self-reported 2. Men: 2% (1–3);<br />
1058 women ‘frequent’ or women: 10% (8–11)<br />
(25–29 years) ‘constant’<br />
Probert et al, 1995 731 women 1. Symptoms 1. 8.2% (6–10)<br />
(25–69 years) (Rome criteria)<br />
2. Self-perceived 2. 8.5% (7–11)<br />
Older people<br />
Thompson & Heaton, 1980 <strong>Health</strong>y adults Stra<strong>in</strong><strong>in</strong>g at stool 20% (12–28)<br />
(60–91 years)<br />
n = 100<br />
Heaton & Cripps, 1993; General population; Stra<strong>in</strong><strong>in</strong>g to start Men: 14% (7–21);<br />
Heaton et al, 1993 181 men, 84 women women: 23% (17–29)<br />
(60–69 years)<br />
Donald et al, 1985 <strong>Elderly</strong> liv<strong>in</strong>g at home, 1. Self-reported 1. 23% (16–30)<br />
sampled from general constipation<br />
practitioner register 2. Stra<strong>in</strong><strong>in</strong>g 2. 25% (18–33)<br />
(Mean age 76 years)<br />
n = 129<br />
Rome criteria (Probert et al, 1995). The prevalence<br />
<strong>of</strong> self-reported frequent constipation <strong>in</strong> men<br />
appears to be much lower – about 2% (Heaton<br />
& Cripps, 1993).<br />
Prevalence <strong>of</strong> constipation <strong>in</strong><br />
<strong>the</strong> elderly<br />
Constipation appears to be a greater problem<br />
<strong>in</strong> elderly people. Not only does <strong>the</strong> prevalence<br />
appear to be much higher <strong>in</strong> this age group<br />
but <strong>the</strong> impact on quality <strong>of</strong> life is greater.<br />
There have been a small number <strong>of</strong> UK<br />
surveys which have estimated <strong>the</strong> prevalence<br />
<strong>of</strong> constipation <strong>in</strong> <strong>the</strong> elderly. These surveys<br />
are categorised below accord<strong>in</strong>g to whe<strong>the</strong>r<br />
<strong>the</strong> participants were liv<strong>in</strong>g ei<strong>the</strong>r <strong>in</strong> <strong>the</strong><br />
community or <strong>in</strong> some form <strong>of</strong> <strong>in</strong>stitution<br />
(<strong>in</strong>clud<strong>in</strong>g hospitals).<br />
Prevalence <strong>of</strong> constipation <strong>in</strong> elderly<br />
people liv<strong>in</strong>g <strong>in</strong> <strong>the</strong> community<br />
Estimates <strong>of</strong> <strong>the</strong> prevalence <strong>of</strong> constipation<br />
<strong>in</strong> elderly people liv<strong>in</strong>g <strong>in</strong> private households<br />
are available from several UK surveys (Table 1).<br />
Some <strong>of</strong> <strong>the</strong>se allow direct comparisons with <strong>the</strong><br />
prevalence <strong>in</strong> younger age groups <strong>in</strong> <strong>the</strong> same<br />
survey. For example, <strong>in</strong> Thompson and Heaton’s<br />
(1980) survey <strong>of</strong> 301 apparently healthy adults,<br />
constipation (def<strong>in</strong>ed as stra<strong>in</strong><strong>in</strong>g at stool) was<br />
reported significantly more <strong>of</strong>ten by elderly<br />
respondents (20% ± 8%) than by middle-aged<br />
(8%) and younger (3%) respondents. In <strong>the</strong>ir<br />
UK survey, Heaton and Cripps (1993) also found<br />
<strong>the</strong> prevalence <strong>of</strong> reported stra<strong>in</strong><strong>in</strong>g to <strong>in</strong>crease