Effectiveness of Laxatives in the Elderly - NIHR Health Technology ...
Effectiveness of Laxatives in the Elderly - NIHR Health Technology ...
Effectiveness of Laxatives in the Elderly - NIHR Health Technology ...
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Appendix 3<br />
<strong>Health</strong> <strong>Technology</strong> Assessment 1997; Vol. 1: No. 13<br />
Effect size by quality score for adult trials<br />
identified by Cochrane review (exclud<strong>in</strong>g trials<br />
<strong>in</strong> <strong>the</strong> elderly)<br />
4.0<br />
3.5<br />
3.0<br />
2.5<br />
2.0<br />
1.5<br />
1.0<br />
0.5<br />
0<br />
1<br />
Change <strong>in</strong> BMs per week<br />
2 3 4 5 6 7<br />
Quality score<br />
This graph <strong>of</strong> effect sizes (<strong>in</strong> bowel movements per week) from <strong>the</strong> trials <strong>of</strong> laxatives <strong>in</strong> adults shows<br />
an apparently higher effect size <strong>in</strong> higher quality trials. The implication is that poorer quality trials<br />
may underestimate <strong>the</strong> effects <strong>of</strong> treatment (but see page 27).<br />
49
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