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Effectiveness of Laxatives in the Elderly - NIHR Health Technology ...

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46<br />

Appendix 1<br />

Pre-def<strong>in</strong>ed search strategy for<br />

reviews/RCTs<br />

(i) Search performed: 1 and 2 and 3 and 4 and 5.<br />

This result was NOT be limited to English<br />

language publications only.<br />

Exclude PREGNANCY.<br />

(ii) Fluid <strong>the</strong>rapy <strong>in</strong> constipation<br />

Explode CONSTIPATION/all subhead<strong>in</strong>gs<br />

This was comb<strong>in</strong>ed with <strong>the</strong> follow<strong>in</strong>g terms<br />

to pick up all studies (<strong>in</strong>clud<strong>in</strong>g reviews)<br />

referr<strong>in</strong>g to fluid <strong>the</strong>rapy:<br />

FLUID<br />

FLUIDS<br />

HYDRATION<br />

REHYDRATION<br />

FLUID or FLUIDS or HYDRATION<br />

or REHYDRATION<br />

FLUID-THERAPY<br />

This strategy produced 54 hits. A total<br />

<strong>of</strong> 18 papers exam<strong>in</strong>ed <strong>the</strong> role <strong>of</strong> fluid<br />

<strong>in</strong> constipation. Of <strong>the</strong>se, 11 were reviews<br />

mention<strong>in</strong>g <strong>the</strong> importance <strong>of</strong> fluid<br />

<strong>in</strong>take. One was a survey, one a casecontrol<br />

study <strong>of</strong> risk factors for<br />

constipation. The rema<strong>in</strong><strong>in</strong>g five studies<br />

were non-comparative studies <strong>of</strong><br />

fluid <strong>the</strong>rapy, <strong>in</strong> all <strong>of</strong> which fluid<br />

<strong>in</strong>take was altered <strong>in</strong> addition to<br />

dietary changes (e.g. by<br />

add<strong>in</strong>g fibre).<br />

(iii) Exercise <strong>the</strong>rapy <strong>in</strong> constipation<br />

The term constipation and its subhead<strong>in</strong>gs<br />

were comb<strong>in</strong>ed with ei<strong>the</strong>r<br />

EXERCISE or EXERCISE-THERAPY<br />

or MOBILITY. This produce eight hits,<br />

none <strong>of</strong> which were studies <strong>of</strong> <strong>the</strong> use<br />

<strong>of</strong> exercise <strong>the</strong>rapy <strong>in</strong> constipation.

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