Lecture 7 - Genome Tools

•Activation of Toll by Spatzel leads to
•Gradient of Dorsal:
ventrally high and dorsally low.
•[Dorsal] not high enough to bind to
•low affin twist/snail; binds to
•High affin rhomboid with activator bHLH.
•Sharp boundary of Rhomboiddistinct
cell types.
•And....
Spatzel binds Toll....