Lecture 7 - Genome Tools
Lecture 7 - Genome Tools
Lecture 7 - Genome Tools
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Interacting or redundant proteins, compensating mutants<br />
•Nature of ‘rescue’ vs suppression<br />
•Temperature sensitive mutants<br />
•ACT1 actin<br />
•SAC6 actin-binding protein<br />
•WT: asymmetric distribution<br />
•Each mutant: random distribution<br />
•Dbl mutant: “WT-like”<br />
•(restores function, “suppresses”)
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