A fast, robust and tunable synthetic gene oscillator - The BioCircuits ...
A fast, robust and tunable synthetic gene oscillator - The BioCircuits ...
A fast, robust and tunable synthetic gene oscillator - The BioCircuits ...
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doi: 10.1038/nature07389 SUPPLEMENTARY INFORMATION<br />
Groisman, A., Lobo, C., Cho, H., Campbell, J. K., Dufour, Y. S., Stevens, A. M. <strong>and</strong> Levchenko,<br />
A. (2005). A microfluidic chemostat for experiments with bacterial <strong>and</strong> yeast cells. Nat Methods<br />
2:685–9.<br />
Gutenkunst, R. N., Waterfall, J. J., Casey, F. P., Brown, K. S., Myers, C. R. <strong>and</strong> Sethna, J. P. (2007).<br />
Universally sloppy parameter sensitivities in systems biology models. PLoS Comp Bio 3:1871–<br />
1878.<br />
Kahn, M., Kolter, R., Thomas, C., Figurski, D., Meyer, R., Remaut, E. <strong>and</strong> Helinski, D. R. (1979).<br />
Plasmid cloning vehicles derived from plasmids ColE1, F, R6K, <strong>and</strong> RK2. Methods Enzymol<br />
68:268–280.<br />
Lee, S. K., Chou, H. H., Pfleger, B. F., Newman, J. D., Yoshikuni, Y. <strong>and</strong> Keasling, J. D. (2007).<br />
Directed evolution of arac for improved compatibility of arabinose- <strong>and</strong> lactose-inducible promoters.<br />
Appl Environ Microbiol 73:5711–5715.<br />
Lutz, R. <strong>and</strong> Bujard, H. (1997). Independent <strong>and</strong> tight regulation of transcriptional units in Escherichia<br />
coli via the LacR/O, the TetR/O <strong>and</strong> AraC/I1-I2 regulatory elements. Nucleic Acids Res<br />
25:1203–1210.<br />
Mackey, M. C. <strong>and</strong> Nechaeva, I. G. (1995). Solution moment stability in stochastic differentialdelay<br />
equations. Phys Rev E 52:3366–3376.<br />
Miller, J. H. (1992). A short course in bacterial <strong>gene</strong>tics. Cold Spring Harbor Laboratory Press.<br />
Rateitschak, K. <strong>and</strong> Wolkenhauer, O. (2007). Intracellular delay limits cyclic changes in <strong>gene</strong><br />
expression. Math Biosci 205:163–179.<br />
Shaner, N. C., Steinbach, P. A. <strong>and</strong> Tsien, R. Y. (2005). A guide to choosing fluorescent proteins.<br />
Nat Methods 2:905–909.<br />
Sheff, M. A. <strong>and</strong> Thorn, K. S. (2004). Optimized cassettes for fluorescent protein tagging in Saccharomyces<br />
cerevisiae. Yeast 21:661–670.<br />
Sia, S. K. <strong>and</strong> Whitesides, G. M. (2003). Microfluidic devices fabricated in poly(dimethylsiloxane)<br />
for biological studies. Electrophoresis 24:3563–76.<br />
Siegele, D. A. <strong>and</strong> Hu, J. C. (1997). Gene expression from plasmids containing the araBAD promoter<br />
at subsaturating inducer concentrations represents mixed populations. Proc Natl Acad<br />
Sci U S A 94:8168–8172.<br />
Tesla, N. (1920). U. S. Patent No. 1,329,559.<br />
Unger, M. A., Chou, H. P., Thorsen, T., Scherer, A. <strong>and</strong> Quake, S. R. (2000). Monolithic microfabricated<br />
valves <strong>and</strong> pumps by multilayer soft lithography. Science 288:113–6.<br />
Whitesides, G. M., Ostuni, E., Takayama, S., Jiang, X. <strong>and</strong> Ingber, D. E. (2001). Soft lithography<br />
in biology <strong>and</strong> biochemistry. Annu Rev Biomed Eng 3:335–73.<br />
Zacharias, D. A., Violin, J. D., Newton, A. C. <strong>and</strong> Tsien, R. Y. (2002). Partitioning of lipid-modified<br />
monomeric GFPs into membrane microdomains of live cells. Science 296:913–916.<br />
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