Is Neonatale Screening op Mucoviscidose aangewezen in België?

34 Cystic Fibrosis Neonatal Screening KCE Reports 132
Key Points
• Current guidelines for implementation of CF newborn screening programs
invariably stress the importance of carefully considering each step of the
process, keeping in mind that “No system is stronger than its weakest link”.
It is also necessary to identify and assemble those who will have operational
responsibility.
• Carefully determining the spectrum of CF disease that a NBS program will
aim to identify is one of the first essential tasks.
• Physicians should understand the limits of the screening and remain vigilant
to identify false-negative cases: suggestive symptoms should still lead them
to suspect a diagnosis of cystic fibrosis.
• Quality assurance programs for the sweat test remain a key component of
any CF NBS program.
• Optimized communication at all steps of the process should be fluent.
• Centralization of outcome data from all CF centres should allow a
monitoring structure to evaluate and modify screening algorithms if needed