Bui Lecture.pdf
Bui Lecture.pdf
Bui Lecture.pdf
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Recombinase activating gene-deficient<br />
mice lack T, NK-T, and B cells.<br />
Shankaran et al., Nature 2001<br />
Partially immune deficient<br />
mice develop a higher<br />
incidence of MCA-induced<br />
fibrosarcomas.<br />
Methods: Mice with<br />
different genetic<br />
deficiencies were injected<br />
subcutaneously with 3’methylcholanthrene<br />
and<br />
tumor incidence was<br />
assessed.