New Entities in Smoking Related Lung Disease

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Patterns which denote invasion • Solid with mucin – Including clear cell, signet ring • Papillary • Acinar • Micropapillary (Pathology recommendation 7) – Prognostic data 5/28/2011 14
Pathology Recommendation 4/5 • Comprehensive histologic subtyping used to assess patterns semiquantitatively in 5% increments, choosing a single predominant pattern. • In multiple lung adenocarcinomas, comprehensive histologic subtyping may aid in determining whether tumors are metastases or separate primaries. Lesions larger than 3cm? • The data in the IASLC analysis were for tumors less than 2 or 3 cm. • If greater than 3 cm – “Lepidic predominant adenocarcinoma, suspect AIS or MIA.” – “Lepidic predominant adenocarcinoma.” Am J Surg Pathol. 2009 Dec;33(12):1752-64. 5/28/2011 15
Page 1 and 2: New Entities in Smoking- Related Lu
Page 3 and 4: The Military Experience • Analysi
Page 5 and 6: 5/28/2011 5
Page 7 and 8: Human Pathology 2010; 41: 316-325 S
Page 9 and 10: SRIF - Conclusions • Smoking can
Page 11 and 12: Pathology Recommendations 2/3 • S
Page 13: From Whence “Lepidic” • 1962:
Page 17 and 18: Pathology Recommendation 9/10 • N
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New Entities in Smoking Related Lung Disease

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