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New Entities in Smoking Related Lung Disease

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The Military Experience<br />

• Analysis of 15 different brands of<br />

tobacco available <strong>in</strong> the theater of<br />

operation revealed no unusual<br />

components, tox<strong>in</strong>s, pesticide residues<br />

or significant microbial colonization.<br />

CHEST 2008; 133: 1174-1180<br />

Diagnosis of Eos<strong>in</strong>ophilic<br />

Pneumonia<br />

• Triad of f<strong>in</strong>d<strong>in</strong>gs with<strong>in</strong> airspaces<br />

– Macrophages (often mult<strong>in</strong>ucleate)<br />

– Fibr<strong>in</strong><br />

– Eos<strong>in</strong>ophils<br />

• Often, the clue will be the macrophages<br />

rather than the eos<strong>in</strong>ophils<br />

• Be aware of steroid adm<strong>in</strong>istration<br />

– Hypereos<strong>in</strong>ophilic, granular fibr<strong>in</strong><br />

5/28/2011<br />

3

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